Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

Chemodynamic therapy (CDT) has emerged to be a frontrunner amongst reactive oxygen
species‐based cancer treatment modalities. CDT utilizes endogenous H2O2 in tumor …

Although ferroptosis therapy has been proven to be a promising strategy for cancer
treatment, its efficacy still might be limited by insufficient H2O2 supply in tumor tissue …

Despite the promise of sonodynamic processes in cancer therapy, existing sonosensitizers
often fail to regulate the generation of reactive oxygen species (ROS) against tumors …

The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …

The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

The use of nanomedicine for cancer treatment takes advantage of its preferential
accumulation in tumors owing to the enhanced permeability and retention (EPR) effect. The …

Multiple enzyme‐driven biological catalytic cascades occur in living organisms, guiding
highly efficient and selective transformations of substrates. Inspired by the merits of these …

Lactate in tumors has long been considered “metabolic junk” derived from the glycolysis of
cancer cells and utilized only as a biomarker of malignancy, but is presently believed to be a …

Sonodynamic therapy (SDT) is a promising cancer therapy due to its noninvasiveness,
negligible side effects, and deep tissue penetration. However, the effect of SDT is …