The glucocorticoid receptor (GR) is crucial for the effects of glucocorticoids (GCs). Several
polymorphisms of the GR are associated with altered sensitivity to GCs. For the ER22/23EK …

Cortisol is involved in many physiological processes, including immunosuppressive and anti-
inflammatory actions, and therefore cortisol and its synthetic analogs are widely used to treat …

Glucocorticoids (GCs) are steroid hormones that influence several physiologic functions and
are among the most frequently prescribed drugs worldwide. Resistance to GCs has been …

Object Although glucocorticoids are essential for health, several studies have shown that
glucocorticoids replacement in Addison's disease might be involved in anthropometric and …

Glucocorticoids exert pleiotropic effects on all tissues to regulate cellular and metabolic
homeostasis. Synthetic forms are used therapeutically in a wide range of conditions for their …

Objective Glucocorticoid substitution is essential in patients with chronic primary
adrenocortical insufficiency (Addison's disease) and both over‐treatment and inadequate …

The survival rates in childhood acute lymphoid leukemia (ALL) have improved dramatically;
however, patients still suffer from a variety of drug-related toxicities. Individualized therapy …

Context Single-tier newborn screening (NBS) for congenital adrenal hyperplasia (CAH)
using 17-hydroxyprogesterone (17OHP) measured by fluoroimmunoassay (FIA) in samples …

Background Lifelong glucocorticoid (GC) replacement is the mainstay treatment of
congenital adrenal hyperplasia (CAH) due to classic 21-hydroxylase deficiency (21-OHD) …

OBJECTIVE: A single-nucleotide polymorphism (SNP), the G variant in codon 1013
(GAA1013→ GAG) of the insulin-like growth factor-1 (IGF-1) receptor (IGFIR) gene, has been …