Abstract The US Food and Drug Administration approval of the first 3D printed tablet in 2015
has ignited growing interest in 3D printing, or additive manufacturing (AM), for drug delivery …

Patient to patient variability is one of the issues when administering medications to
individuals with different health conditions, pharmacokinetic, age, fitness, gender, and race …

Could nose-to-brain pathways mediate the effects of peptides such as oxytocin (OT) on brain
physiology when delivered intranasally? We address this question by contrasting two …

Central nervous system (CNS) disorders, such as psychiatric disorders, neurodegeneration,
chronic pain, stroke, brain tumor, spinal cord injury, and many other CNS diseases, would …

Acetylcholinesterase inhibitors are the most used drugs to manage Alzheimer's disease,
although they show low bioavailability in the brain. In this sense, nasal administration has …

The nasal cavity is an attractive route for both local and systemic drug delivery and holds
great potential for access to the brain via the olfactory region, an area where the blood–brain …

The nasal route has been used for many years for the local treatment of nasal diseases.
More recently, this route has been gaining momentum, due to the possibility of targeting the …

Background In nasal drug delivery system, nasal spray seems to be the most promising
delivery method for both local and systemic diseases therapy. Nasal deposition behavior is …

The nose is the initial site of viral infection, replication, and transmission in the human body.
Nasally inhaled vaccines may act as a promising alternative for COVID‐19 management in …

Nasal delivery offers many benefits over other conventional routes of delivery (eg oral or
intravenous administration). Benefits include, among others, a fast onset of action, non …