Physical models of collective cell migration
Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
Continuum models of collective cell migration
S Banerjee, MC Marchetti - Cell migrations: Causes and functions, 2019 - Springer
Collective cell migration plays a central role in tissue development, morphogenesis, wound
repair and cancer progression. With the growing realization that physical forces mediate cell …
repair and cancer progression. With the growing realization that physical forces mediate cell …
Active wetting of epithelial tissues
Abstract Development, regeneration and cancer involve drastic transitions in tissue
morphology. In analogy with the behaviour of inert fluids, some of these transitions have …
morphology. In analogy with the behaviour of inert fluids, some of these transitions have …
Collective cell migration without proliferation: density determines cell velocity and wave velocity
Collective cell migration contributes to embryogenesis, wound healing and tumour
metastasis. Cell monolayer migration experiments help in understanding what determines …
metastasis. Cell monolayer migration experiments help in understanding what determines …
Active fingering instability in tissue spreading
R Alert, C Blanch-Mercader, J Casademunt - Physical review letters, 2019 - APS
During the spreading of epithelial tissues, the advancing tissue front often develops
fingerlike protrusions. Their resemblance to traditional viscous fingering patterns in driven …
fingerlike protrusions. Their resemblance to traditional viscous fingering patterns in driven …
Role of the cell cycle in collective cell dynamics
Cells coexist together in colonies or as tissues. Their behavior is controlled by an interplay
between intercellular forces and biochemical regulation. We develop a simple model of the …
between intercellular forces and biochemical regulation. We develop a simple model of the …
Control of cell colony growth by contact inhibition
Contact inhibition is a cell property that limits the migration and proliferation of cells in
crowded environments. Here we investigate the growth dynamics of a cell colony composed …
crowded environments. Here we investigate the growth dynamics of a cell colony composed …
From cells to tissue: A continuum model of epithelial mechanics
S Ishihara, P Marcq, K Sugimura - Physical Review E, 2017 - APS
A two-dimensional continuum model of epithelial tissue mechanics was formulated using
cellular-level mechanical ingredients and cell morphogenetic processes, including cellular …
cellular-level mechanical ingredients and cell morphogenetic processes, including cellular …
Role of substrate stiffness in tissue spreading: Wetting transition and tissue durotaxis
R Alert, J Casademunt - Langmuir, 2018 - ACS Publications
Living tissues undergo wetting transitions: On a surface, they can either form a dropletlike
cell aggregate or spread as a monolayer of migrating cells. Tissue wetting depends not only …
cell aggregate or spread as a monolayer of migrating cells. Tissue wetting depends not only …
Competition between cell types under cell cycle regulation with apoptosis
Competition between different cell types plays a crucial role in bacterial ecology,
developmental biology, and tumor growth. We study how cells compete in 2D by using both …
developmental biology, and tumor growth. We study how cells compete in 2D by using both …