[HTML][HTML] Ventilator-associated pneumonia: present understanding and ongoing debates

GB Nair, MS Niederman - Intensive care medicine, 2015 - Springer
Introduction Ventilator-associated pneumonia (VAP) is a common cause of nosocomial
infection, and is related to significant utilization of health-care resources. In the past decade …

[HTML][HTML] New antibiotics for hospital-acquired pneumonia and ventilator-associated pneumonia

M Bassetti, A Mularoni, DR Giacobbe… - … in respiratory and …, 2022 - thieme-connect.com
Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) represent
one of the most common hospital-acquired infections, carrying a significant morbidity and …

Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America …

AC Kalil, ML Metersky, M Klompas… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Multicentre evaluation of two multiplex PCR platforms for the rapid microbiological investigation of nosocomial pneumonia in UK ICUs: the INHALE WP1 study

VI Enne, A Aydin, R Baldan, DR Owen, H Richardson… - Thorax, 2022 - thorax.bmj.com
Background Culture-based microbiological investigation of hospital-acquired or ventilator-
associated pneumonia (HAP or VAP) is insensitive, with aetiological agents often …

[HTML][HTML] Chinese guidelines for the diagnosis and treatment of hospital-acquired pneumonia and ventilator-associated pneumonia in adults (2018 Edition)

Y Shi, Y Huang, TT Zhang, B Cao, H Wang… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Pneumonia (draft)” was published in 1999 (1). Afterwards, a number of guidelines for
HAP/VAP have been published or updated at home and abroad (2-10). The definitions of …

[HTML][HTML] Prognostic factors associated with mortality of drug-resistant Acinetobacter baumannii ventilator-associated pneumonia

J Inchai, C Pothirat, C Bumroongkit, A Limsukon… - Journal of intensive …, 2015 - Springer
Background Ventilator-associated pneumonia (VAP) caused by drug-resistant Acinetobacter
baumannii is associated with high mortality in critically ill patients. We identified the …

Advantages and challenges of metagenomic sequencing for the diagnosis of pulmonary infectious diseases

Y Chen, LC Fan, YH Chai, JF Xu - The Clinical Respiratory …, 2022 - Wiley Online Library
Objective We aim to familiarize the application status of metagenomic sequencing in
diagnosing pulmonary infections, to compare metagenomic sequencing with traditional …

Interaction of Drug- and Granulocyte-Mediated Killing of Pseudomonas aeruginosa in a Murine Pneumonia Model

GL Drusano, W Liu, S Fikes, R Cirz… - The Journal of …, 2014 - academic.oup.com
Background. Killing of bacterial pathogens by granulocytes is a saturable process, as
previously demonstrated. There is virtually no quantitative information about how …

Update on management options in the treatment of nosocomial and ventilator assisted pneumonia: review of actual guidelines and economic aspects of therapy

M Wilke, R Grube - Infection and drug resistance, 2013 - Taylor & Francis
Objective Nosocomial or more exactly, hospital-acquired (HAP) and ventilator-associated
pneumonia (VAP) are frequent conditions when treating intensive care unit (ICU) patients …

[HTML][HTML] Weighted-incidence syndromic combination antibiograms to guide empiric treatment of critical care infections: a retrospective cohort study

V Randhawa, S Sarwar, S Walker, M Elligsen… - Critical care, 2014 - Springer
Introduction Empiric antimicrobial selection for critical care infections must balance the need
for timely adequate coverage with the resistance pressure exerted by broadspectrum …