Can we microbe-manage our vitamin acquisition for better health?
J Nysten, P Van Dijck - Plos Pathogens, 2023 - journals.plos.org
Vitamins are indispensable micronutrients that are needed for a myriad of metabolic and
regulatory processes critical for all living organisms [1–3]. Because humans do not have the …
regulatory processes critical for all living organisms [1–3]. Because humans do not have the …
Enzymes in riboflavin biosynthesis: Potential antibiotic drug targets
The rapid resistance of pathogens to antibiotics has emerged as a major threat to global
health. Identification of new antibiotic targets is thus needed for developing alternative …
health. Identification of new antibiotic targets is thus needed for developing alternative …
From Metabolism to Vitality: Uncovering Riboflavin's Importance in Poultry Nutrition
Y Shastak, W Pelletier - Animals, 2023 - mdpi.com
Simple Summary Riboflavin, an essential B-vitamin, plays a crucial role in poultry
metabolism, impacting energy production, growth, and immune regulation. Its role in redox …
metabolism, impacting energy production, growth, and immune regulation. Its role in redox …
Mutation of the Plasmodium falciparum Flavokinase Confers Resistance to Roseoflavin and 8-Aminoriboflavin
The riboflavin analogues, roseoflavin and 8-aminoriboflavin, inhibit malaria parasite
proliferation by targeting riboflavin utilization. To determine their mechanism of action, we …
proliferation by targeting riboflavin utilization. To determine their mechanism of action, we …
Identification and characterization of thiamine analogs with antiplasmodial activity
I Fathoni, TCS Ho, AHY Chan, FJ Leeper… - Antimicrobial Agents …, 2024 - journals.asm.org
Thiamine is metabolized into thiamine pyrophosphate (TPP), an essential enzyme cofactor.
Previous work has shown that oxythiamine, a thiamine analog, is metabolized by thiamine …
Previous work has shown that oxythiamine, a thiamine analog, is metabolized by thiamine …
Analysis of complementarities between nanomedicine and phytodrugs for the treatment of malarial infection
F Fulgheri, ML Manca, X Fernàndez-Busquets… - …, 2023 - Taylor & Francis
The use of nanocarriers in medicine, so-called nanomedicine, is one of the most innovative
strategies for targeting drugs at the action site and increasing their activity index and …
strategies for targeting drugs at the action site and increasing their activity index and …
Role of riboflavin deficiency in malaria pathophysiology
The emergence of resistance against antimalarials and insecticides poses a significant
threat to malaria elimination strategies. It is crucial to explore potential risk factors for malaria …
threat to malaria elimination strategies. It is crucial to explore potential risk factors for malaria …
Mutation of the P. falciparum flavokinase confers resistance to roseoflavin and 8-aminoriboflavin
We previously found that two riboflavin analogues, roseoflavin and 8-aminoriboflavin, inhibit
malaria parasite proliferation by targeting riboflavin utilisation. To determine the mechanism …
malaria parasite proliferation by targeting riboflavin utilisation. To determine the mechanism …