Placental function in maternal obesity

AC Kelly, TL Powell, T Jansson - Clinical Science, 2020 - portlandpress.com
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …

The obese brain: mechanisms of systemic and local inflammation, and interventions to reverse the cognitive deficit

V Salas-Venegas, RP Flores-Torres… - Frontiers in Integrative …, 2022 - frontiersin.org
Overweight and obesity are now considered a worldwide pandemic and a growing public
health problem with severe economic and social consequences. Adipose tissue is an organ …

The effects of obesity on anti-cancer immunity and cancer immunotherapy

MJ Woodall, S Neumann, K Campbell, ST Pattison… - Cancers, 2020 - mdpi.com
Cancer is one of the leading causes of morbidity and mortality worldwide. Traditional
treatments include surgery, chemotherapy and radiation therapy, and more recently targeted …

Stress granules determine the development of obesity-associated pancreatic cancer

G Fonteneau, A Redding, H Hoag-Lee, ES Sim… - Cancer discovery, 2022 - AACR
Obesity is a global epidemic and a major predisposing factor for cancer. Increasing
evidence shows that obesity-associated stress is a key driver of cancer risk and progression …

Single 30 min treadmill exercise session suppresses the production of pro-inflammatory cytokines and oxidative stress in obese female adolescents

A Pranoto, PS Rejeki, M Miftahussurur… - Journal of basic and …, 2023 - degruyter.com
Objectives Regular treadmill exercise may result in changes in pro-inflammatory cytokines
and oxidative stress. However, the way acute treadmill exercise mechanisms affect the …

Elevated adipose tissue associated IL-2 expression in obesity correlates with metabolic inflammation and insulin resistance

S Kochumon, A Al Madhoun, F Al-Rashed, R Thomas… - Scientific reports, 2020 - nature.com
Adipose tissue (AT) associated cytokines are involved in the development of chronic low-
grade inflammation in obese individuals. IL-2, a pleiotropic cytokine, contributes to immune …

Physiological changes and pathological pain associated with sedentary lifestyle-induced body systems fat accumulation and their modulation by physical exercise

E Verdú, J Homs, P Boadas-Vaello - International journal of …, 2021 - mdpi.com
A sedentary lifestyle is associated with overweight/obesity, which involves excessive fat
body accumulation, triggering structural and functional changes in tissues, organs, and body …

Association between Irisin, hs‐CRP, and metabolic status in children and adolescents with type 2 diabetes mellitus

L Elizondo-Montemayor… - Mediators of …, 2019 - Wiley Online Library
Proinflammatory cytokines and the novel myokine irisin, a cleavage product of FNDC5, have
been found to play a role in obesity and type 2 diabetes mellitus (T2DM). Irisin has been …

Inflammatory cytokine profiles in visceral and subcutaneous adipose tissues of obese patients undergoing bariatric surgery reveal lack of correlation with obesity or …

V Rakotoarivelo, G Lacraz, M Mayhue, C Brown… - …, 2018 - thelancet.com
Population studies have linked insulin resistance to systemic low-grade chronic
inflammation and have reported elevated levels of inflammatory cytokines such as TNFα, IL …

Cytokines and the immune response in obesity-related disorders

M Moghbeli, H Khedmatgozar, M Yadegari… - Advances in clinical …, 2021 - Elsevier
The increasing prevalence of obesity and the associated morbidity and mortality are
important public health problems globally. There is an important relationship between an …