[HTML][HTML] Enteroviruses and T1D: is it the virus, the genes or both which cause T1D

S Geravandi, H Liu, K Maedler - Microorganisms, 2020 - mdpi.com
Type 1 diabetes (T1D) is a chronic autoimmune disorder that results from the selective
destruction of insulin-producing β-cells in the pancreas. Up to now, the mechanisms …

Enteroviruses as causative agents in type 1 diabetes: loose ends or lost cause?

NG Morgan, SJ Richardson - Trends in Endocrinology & Metabolism, 2014 - cell.com
Considerable evidence implies that an enteroviral infection may accelerate or precipitate
type 1 diabetes (T1D) in some individuals. However, causality is not proven. We present and …

Expression of interferon-stimulated genes in insulitic pancreatic islets of patients recently diagnosed with type 1 diabetes

M Lundberg, L Krogvold, E Kuric, K Dahl-Jørgensen… - Diabetes, 2016 - Am Diabetes Assoc
A primary insult to the pancreatic islets of Langerhans, leading to the activation of innate
immunity, has been suggested as an important step in the inflammatory process in type 1 …

[HTML][HTML] Localization of enteroviral RNA within the pancreas in donors with T1D and T1D-associated autoantibodies

S Geravandi, S Richardson, A Pugliese, K Maedler - Cell Reports Medicine, 2021 - cell.com
Enteroviral infections have been associated with autoimmunity and type 1 diabetes (T1D),
but reliable methods to ascertain localization of single infected cells in the pancreas were …

[HTML][HTML] Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using short fluorescently-labelled oligonucleotide probes

N Busse, F Paroni, SJ Richardson, JE Laiho… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using
short fluorescently-labelled oligonucleotide probes - PMC Back to Top Skip to main content NIH …

Novel pathologic findings and viral antigen distribution in cattle and buffalo calves naturally infected with Foot-and-Mouth disease virus

M Sahoo, R Singh, P Kumar… - Veterinary …, 2023 - Taylor & Francis
Abstract The Foot-and-Mouth disease is highly contagious acute viral disease of livestock
inflicting huge economic loss to the farmers. The limited knowledge regarding the …

[HTML][HTML] Enteroviral infections are not associated with type 2 diabetes

H Liu, S Geravandi, AM Grasso, S Sikdar… - Frontiers in …, 2023 - frontiersin.org
Introduction For more than a century, enteroviral infections have been associated with
autoimmunity and type 1 diabetes (T1D). Uncontrolled viral response pathways repeatedly …

Preparation and verification of a monoclonal antibody against a conserved linear epitope in enterovirus A protein 2C

L Liu, M Wang, R Yu, H Li, J Fan, J Yan, Z Liu… - Journal of Virological …, 2021 - Elsevier
Abstract Enterovirus A (EV-A) species are the main agents responsible for hand, foot, and
mouth disease (HFMD), a serious public health concern. Lack of appropriate reagents …

[HTML][HTML] Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

O Skog, K Klingel, M Roivainen, O Korsgren - Diabetologia, 2019 - Springer
To the Editor: We read with great interest the For Debate article by Dunne et al [1] and fully
agree with the conclusion that intervention studies using a vaccine or antiviral drugs …

Presence of Human Herpesvirus 6B in the Pancreas of Subjects with and without Type 1 Diabetes

M Ericsson, O Skog - Pancreas, 2017 - journals.lww.com
Objectives The aims of this study were to investigate the presence of human herpesvirus 6
(HHV6) A and B in human pancreata and to search for signs of active infection in this organ …