Does this patient need blood cultures? A scoping review of indications for blood cultures in adult nonneutropenic inpatients

V Fabre, SL Sharara, AB Salinas… - Clinical Infectious …, 2020 - academic.oup.com
Guidance regarding indications for initial or follow-up blood cultures is limited. We
conducted a scoping review of articles published between January 2004 and June 2019 that …

Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

SL Weiss, MJ Peters, W Alhazzani, MSD Agus… - Intensive care …, 2020 - Springer
Objectives To develop evidence-based recommendations for clinicians caring for children
(including infants, school-aged children, and adolescents) with septic shock and other …

What is the utility of measuring lactate levels in patients with sepsis and septic shock?

J Weinberger, M Klompas… - Seminars in Respiratory …, 2021 - thieme-connect.com
Elevations in blood lactate concentrations have been studied in sepsis and other disease
states for decades and are well known to be associated with increased mortality. Many …

" The human body is a black box" supporting clinical decision-making with deep learning

M Sendak, MC Elish, M Gao, J Futoma… - Proceedings of the …, 2020 - dl.acm.org
Machine learning technologies are increasingly developed for use in healthcare. While
research communities have focused on creating state-of-the-art models, there has been less …

Infectious Diseases Society of America position paper: recommended revisions to the national severe sepsis and septic shock early management bundle (SEP-1) …

C Rhee, K Chiotos, SE Cosgrove… - Clinical Infectious …, 2021 - academic.oup.com
Abstract The Centers for Medicare & Medicaid Services' Severe Sepsis and Septic Shock
Early Management Bundle (SEP-1) measure has appropriately established sepsis as a …

[HTML][HTML] Effects of compliance with the early management bundle (SEP-1) on mortality changes among medicare beneficiaries with sepsis: a propensity score matched …

SR Townsend, GS Phillips, R Duseja, L Tefera… - Chest, 2022 - Elsevier
Background US hospitals have reported compliance with the SEP-1 quality measure to
Medicare since 2015. Finding an association between compliance and outcomes is …

Association between implementation of the severe sepsis and septic shock early management bundle performance measure and outcomes in patients with suspected …

C Rhee, T Yu, R Wang, SS Kadri, D Fram… - JAMA network …, 2021 - jamanetwork.com
Importance In October 2015, the Centers for Medicare & Medicaid Services began requiring
US hospitals to report adherence to the Severe Sepsis and Septic Shock Early Management …

Risk of misleading conclusions in observational studies of time-to-antibiotics and mortality in suspected sepsis

TR Pak, J Young, CS McKenna, A Agan… - Clinical Infectious …, 2023 - academic.oup.com
Background Influential studies conclude that each hour until antibiotics increases mortality in
sepsis. However, these analyses often (1) adjusted for limited covariates,(2) included …

DeepAISE–An interpretable and recurrent neural survival model for early prediction of sepsis

SP Shashikumar, CS Josef, A Sharma… - Artificial intelligence in …, 2021 - Elsevier
Sepsis, a dysregulated immune system response to infection, is among the leading causes
of morbidity, mortality, and cost overruns in the Intensive Care Unit (ICU). Early prediction of …

Treatment patterns and clinical outcomes after the introduction of the Medicare sepsis performance measure (SEP-1)

IJ Barbash, BS Davis, JG Yabes… - Annals of internal …, 2021 - acpjournals.org
Background: Medicare requires that hospitals report on their adherence to the Severe
Sepsis and Septic Shock Early Management Bundle (SEP-1). Objective: To evaluate the …