Simple Summary Growth factors are hormone-like molecules able to promote division and
migration of normal cells, but cancer captured the underlying mechanisms to unleash tumor …

The epidermal growth factor (EGF) system has allowed chemists, biologists, and clinicians to
improve our understanding of cell production and cancer therapy. The discovery of EGF led …

Abstract Prominin 1 (PROM1) is considered a biomarker for cancer stem cells, although its
biological role is unclear. Prominin 2 (PROM2) has also been associated with certain …

Background In systemic lupus erythematosus (SLE), immune complexes (ICs) containing
self-derived nucleic acids trigger the synthesis of proinflammatory cytokines by immune …

Background No curative therapy is currently available for metastatic prostate cancer (PCa).
The diverse mechanisms of progression include fibroblast growth factor (FGF) axis …

Background Genome-wide association studies (GWASes) have identified many noncoding
germline single-nucleotide polymorphisms (SNPs) that are associated with an increased risk …

Little is known about the signaling network responsible for the organization of the
perinuclear actin cap, a recently identified structure holding unique roles in the regulation of …

Background Lung adenocarcinoma (LUAD) is the most common histological subtype of lung
cancer, with a poor prognosis. The roles of circular RNAs (circRNAs) in tumors have been …

Fascin is an actin-bundling protein that is critical for filopodial formation and other cellular
cytoskeletal structures. An elevated expression of fascin has been observed in tumor cells …

Lung cancer is one of the most common malignant tumor types and the leading cause of
cancer-associated death worldwide. Different types of lung cancer exhibit differences in …