Background—Despite rapid clinical translation and widespread enthusiasm, the therapeutic
benefits of adult bone marrow cell (BMC) transplantation in patients with ischemic heart …

Background A promising approach to the treatment of chronic ischaemic heart disease and
congestive heart failure is the use of stem cells. The last decade has seen a plethora of …

Context Previous studies using autologous bone marrow mononuclear cells (BMCs) in
patients with ischemic cardiomyopathy have demonstrated safety and suggested efficacy …

Rationale: A growing number of patients with coronary disease have refractory angina.
Preclinical and early-phase clinical data suggest that intramyocardial injection of autologous …

Aims Adipose-derived regenerative cells (ADRCs) can be isolated from liposuction aspirates
and prepared as fresh cells for immediate administration in cell therapy. We performed the …

Coronary artery disease (CAD) is one of the most common causes of death worldwide. In the
last decade, significant advancements in CAD treatment have been made. The existing …

Rationale: Notwithstanding the uncertainties about the outcomes of bone marrow cell (BMC)
therapy for heart repair, further insights are critically needed to improve this promising …

Based on the increasingly understood regenerative capacity of the human heart and
vascular system, 1 cardiovascular regenerative medicine (CRM) encompasses all potential …

In the absence of effective endogenous repair mechanisms after cardiac injury, cell-based
therapies have rapidly emerged as a potential novel therapeutic approach in ischaemic …

Randomized, controlled clinical trials have demonstrated that cell therapy can improve the
recovery of cardiac function in patients after acute myocardial infarction (AMI). Trial results …