[HTML][HTML] Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis

AS Nagle, S Khare, AB Kumar, F Supek… - Chemical …, 2014 - ACS Publications
Leishmaniasis is a parasitic disease that presents four main clinical syndromes: cutaneous
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …

[HTML][HTML] Marine sponges as a drug treasure

K Anjum, SQ Abbas, SAA Shah, N Akhter… - Biomolecules & …, 2016 - ncbi.nlm.nih.gov
Marine sponges have been considered as a drug treasure house with respect to great
potential regarding their secondary metabolites. Most of the studies have been conducted …

Marine pharmacology in 2007–8: Marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and …

AMS Mayer, AD Rodríguez, RGS Berlinck… - … and Physiology Part C …, 2011 - Elsevier
The peer-reviewed marine pharmacology literature in 2007–8 is covered in this review,
which follows a similar format to the previous 1998–2006 reviews of this series. The …

Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2010 - pubs.rsc.org
Covering: 2008. Previous review: Nat. Prod. Rep., 2009, 26, 170This review covers the
literature published in 2008 for marine natural products, with 829 citations (613 for the …

Antileishmanial drug discovery: Comprehensive review of the last 10 years

JN Sangshetti, FAK Khan, AA Kulkarni, R Arote… - Rsc Advances, 2015 - pubs.rsc.org
Leishmaniasis, a group of diseases caused by hemoflagellate obligate intracellular protozoa
(trypanosomatids) from the genus Leishmania, has not received the attention it deserves …

The isolation of water-soluble natural products–challenges, strategies and perspectives

RGS Berlinck, CM Crnkovic, JR Gubiani… - Natural Product …, 2022 - pubs.rsc.org
Covering period: up to 2019 Water-soluble natural products constitute a relevant group of
secondary metabolites notably known for presenting potent biological activities. Examples …

[HTML][HTML] Current approaches to discover marine antileishmanial natural products

AG Tempone, CM de Oliveira, RGS Berlinck - Planta medica, 2011 - thieme-connect.com
Leishmaniasis is a neglected infectious disease caused by kinetoplastid protozoans. An
urgent need for novel chemotherapeutics exists. The current approaches to discover new …

Phenanthrene, 9, 10-dihydrophenanthrene and bibenzyl enantiomers from Bletilla striata with their antineuroinflammatory and cytotoxic activities

MH Sun, XJ Ma, SY Shao, SW Han, JW Jiang… - Phytochemistry, 2021 - Elsevier
Thirteen undescribed phenanthrene and bibenzyl derivatives, named blestanols AM,
including one pair of biphenanthrene enantiomers, two bis 9, 10-dihydrophenanthrene …

Marine invertebrate natural products for anti‐inflammatory and chronic diseases

K Senthilkumar, SK Kim - Evidence‐Based Complementary …, 2013 - Wiley Online Library
The marine environment represents a relatively available source of functional ingredients
that can be applied to various aspects of food processing, storage, and fortification …

[HTML][HTML] Inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-activated murine macrophage RAW 264.7 cells by the norsesterterpene peroxide …

S Cheenpracha, EJ Park, B Rostama, JM Pezzuto… - Marine drugs, 2010 - mdpi.com
Seven norsesterterpene peroxides: epimuqubilin A (1), muqubilone B (2), unnamed cyclic
peroxide ester (3), epimuqubilin B (4), sigmosceptrellin A methyl ester (5), sigmosceptrellin …