Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …

Once regarded obscure and underappreciated, the gut microbiota (the microbial
communities colonizing the gastrointestinal tract) is gaining recognition as an influencer of …

Phenolic compounds might modulate adiposity. Here, we report our observation that
polyphenols and phenolic acids inhibit adipogenesis in 3T3-L1 with different intensity …

Bile acids are endogenous emulsifiers synthesized from cholesterol having a peculiar
amphiphilic structure. Appreciation of their beneficial effects on human health, recognized …

Introduction: Although pharmacogenetics and pharmacogenomics have been at the forefront
of research aimed at finding novel personalized therapies, the focus of research has recently …

Gut microbiota and bile acids possess the ability to modify absorption and pharmacokinetic
profile of numerous drugs. Since the variability of gliclazide response in patients cannot be …

A major advancement in therapy of type 1 diabetes mellitus (T1DM) is the discovery of new
treatment which avoids and even replaces the absolute requirement for injected insulin. The …

Despite a relatively low prevalence of primary brain tumors, they continuously attract
scientific interest because of the complexity of their treatment due to their location behind the …

Background Gliclazide, a second-generation sulfonylurea derivative still widely used as a
second-line treatment for type 2 diabetes mellitus, is well known to be subject to …

Background Acquiring sufficient knowledge and understanding the importance of intestinal
microbiota and probiotics in health and disease, as well as their potential for interactions …