Biomarkers, designs, and interpretations of resting‐state fMRI in translational pharmacological research: A review of state‐of‐the‐Art, challenges, and opportunities for …
N Khalili‐Mahani, SARB Rombouts… - Human brain …, 2017 - Wiley Online Library
A decade of research and development in resting‐state functional MRI (RSfMRI) has
opened new translational and clinical research frontiers. This review aims to bridge between …
opened new translational and clinical research frontiers. This review aims to bridge between …
MRI assessment of cerebral perfusion in clinical trials
X Wang, C Bishop, J O'Callaghan, A Gayhoor… - Drug Discovery …, 2023 - Elsevier
Highlights•Use of MRI perfusion imaging in clinical trials and as an alternative to other
imaging modalities.•Detailed description of imaging procedures, best practices in clinical …
imaging modalities.•Detailed description of imaging procedures, best practices in clinical …
Calibration of arterial spin labeling data—potential pitfalls in post‐processing
Purpose To assess the impact of the different post‐processing options in the calibration of
arterial spin labeling (ASL) data on perfusion quantification and its reproducibility. Theory …
arterial spin labeling (ASL) data on perfusion quantification and its reproducibility. Theory …
Comparison of arterial spin labeling registration strategies in the multi‐center GENetic frontotemporal dementia initiative (GENFI)
Purpose To compare registration strategies to align arterial spin labeling (ASL) with 3D T1‐
weighted (T1w) images, with the goal of reducing the between‐subject variability of cerebral …
weighted (T1w) images, with the goal of reducing the between‐subject variability of cerebral …
[HTML][HTML] Microvascular impairment in patients with cerebral small vessel disease assessed with arterial spin labeling magnetic resonance imaging: a pilot study
In this pilot study, we investigated microvascular impairment in patients with cerebral small
vessel disease (CSVD) using non-invasive arterial spin labeling (ASL) magnetic resonance …
vessel disease (CSVD) using non-invasive arterial spin labeling (ASL) magnetic resonance …
[HTML][HTML] Short-term apparent brain tissue changes are contributed by cerebral blood flow alterations
Q Ge, W Peng, J Zhang, X Weng, Y Zhang, T Liu… - PloS one, 2017 - journals.plos.org
Structural MRI (sMRI)-identified tissue “growth” after neuropsychological training has been
reported in many studies but the origins of those apparent tissue changes (ATC) still remain …
reported in many studies but the origins of those apparent tissue changes (ATC) still remain …
Assessment of cerebral blood perfusion reserve with acetazolamide using 3D spiral ASL MRI: preliminary experience in pediatric patients
HH Hu, Z Li, AL Pokorney, JM Chia, N Stefani… - Magnetic resonance …, 2017 - Elsevier
Purpose To demonstrate the clinical feasibility of a new non-Cartesian cylindrically-
distributed spiral 3D pseudo-continuous arterial spin labeling (pCASL) magnetic resonance …
distributed spiral 3D pseudo-continuous arterial spin labeling (pCASL) magnetic resonance …
[HTML][HTML] Reliability and reproducibility of Hadamard encoded pseudo-continuous arterial spin labeling in healthy elderly
K Neumann, M Schidlowski, M Günther… - Frontiers in …, 2021 - frontiersin.org
The perfusion parameters cerebral blood flow (CBF) and arterial transit time (ATT) measured
with arterial spin labeling (ASL) magnetic resonance imaging (MRI) provide valuable …
with arterial spin labeling (ASL) magnetic resonance imaging (MRI) provide valuable …
Addressing multi-centre image registration of 3T arterial spin labeling images from the GENetic Frontotemporal dementia Initiative (GENFI)
One obstacle in multi-centre arterial spin labeling (ASL) studies is the variability attributed to
differences between vendor-or site-specific ASL implementations. This multi-centre study …
differences between vendor-or site-specific ASL implementations. This multi-centre study …
Alzheimer's Disease Clinical Trials: What Have We Learned From Magnetic Resonance Imaging
S By, A Kahl, PM Cogswell - Journal of Magnetic Resonance Imaging - Wiley Online Library
Alzheimer's disease (AD) is the leading cause of cognitive impairment and dementia
worldwide with rising prevalence, incidence and mortality. Despite many decades of …
worldwide with rising prevalence, incidence and mortality. Despite many decades of …