Although sleep complaints are often reported in patients with fibromyalgia syndrome (FMS),
there is no conclusive evidence that these complaints represent symptomatic disorders of …

Pain and obesity, as well as their associated impairments, are major health concerns.
Understanding the relationship between the two is the focus of a growing body of research …

Leptin, an appetite-regulatory hormone, is also known to act as a proinflammatory
adipokine. One of the effects of increased systemic leptin concentrations may be greater …

Osteoarthritis (OA) is the most common arthritic disease in the world, leading to debilitating
pain and destruction of joint tissues. While pain is the hallmark symptom of osteoarthritis …

Objective The roles of ghrelin in knee osteoarthritis (OA) are unclear. This study aimed to
examine cross-sectional associations of ghrelin with knee symptoms, joint structures and …

ABSTRACT BACKGROUND AND OBJECTIVES: There are many physiological processes
going on during sleep which are important for physical and emotional balance and …

In this pilot study, a human intravenous injection of low-dose endotoxin (lipopolysaccharide,
LPS) model was used to test if fibromyalgia is associated with altered immune responses to …

Objective Growth hormone (GH) and GH-related signaling molecules play an important role
in nociception and development of chronic pain. This review aims to examine the potential …

The prevalence of overweight and obesity in patients with fibromyalgia is high, which makes
these patients more likely to trigger metabolic changes. It is also uncertain whether the …

There may be a bidirectional relationship between sleep and pain in patients with chronic
pain. Actigraphy is increasingly being used as a non-invasive and objective method to …