[HTML][HTML] Targeted sequencing approach and its clinical applications for the molecular diagnosis of human diseases

XM Pei, MHY Yeung, ANN Wong, HF Tsang, ACS Yu… - Cells, 2023 - mdpi.com
The outbreak of COVID-19 has positively impacted the NGS market recently. Targeted
sequencing (TS) has become an important routine technique in both clinical and research …

Clinical and infection prevention applications of severe acute respiratory syndrome coronavirus 2 genotyping: an Infectious Diseases Society of America/American …

AL Greninger, J Dien Bard, RC Colgrove… - Journal of clinical …, 2022 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged into a world of
maturing pathogen genomics, with more than 2 million genomes sequenced at the time of …

[HTML][HTML] Visceral fat inflammation and fat embolism are associated with lung's lipidic hyaline membranes in subjects with COVID-19

G Colleluori, L Graciotti, M Pesaresi… - International journal of …, 2022 - nature.com
Background Preliminary data suggested that fat embolism could explain the importance of
visceral obesity as a critical determinant of coronavirus disease-2019 (COVID-19). Methods …

Assessment of SARS-CoV-2 genome sequencing: quality criteria and low-frequency variants

D Jacot, T Pillonel, G Greub… - Journal of Clinical …, 2021 - Am Soc Microbiol
Although many laboratories worldwide have developed their sequencing capacities in
response to the need for SARS-CoV-2 genome-based surveillance of variants, only a few …

[HTML][HTML] Novel RT-ddPCR assays for measuring the levels of subgenomic and genomic SARS-CoV-2 transcripts

S Telwatte, HA Martin, R Marczak, P Fozouni… - Methods, 2022 - Elsevier
The replication of SARS-CoV-2 and other coronaviruses depends on transcription of
negative-sense RNA intermediates that serve as the templates for the synthesis of positive …

One-year surveillance of SARS-CoV-2 in wastewater from vulnerable urban communities in metropolitan São Paulo, Brazil

MRF Barbosa, SC Garcia, AC Bruni… - Journal of Water and …, 2022 - iwaponline.com
The current COVID-19 pandemic has emphasized the vulnerability of communities living in
the urban outskirts and informal settlements. The lack of reliable COVID-19 case data …

[HTML][HTML] Pushing the boundaries: forensic DNA phenotyping challenged by single-cell sequencing

M Diepenbroek, B Bayer, K Anslinger - Genes, 2021 - mdpi.com
Single-cell sequencing is a fast developing and very promising field; however, it is not
commonly used in forensics. The main motivation behind introducing this technology into …

[HTML][HTML] SARS-CoV-2 multi-variant rapid detector based on graphene transistor functionalized with an engineered dimeric ACE2 receptor

A Romagnoli, M D'Agostino, E Pavoni, C Ardiccioni… - Nano Today, 2023 - Elsevier
Reliable point-of-care (POC) rapid tests are crucial to detect infection and contain the spread
of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The emergence of …

Alternate primers for whole-genome SARS-CoV-2 sequencing

M Cotten, D Lule Bugembe, P Kaleebu… - Virus …, 2021 - academic.oup.com
As the world is struggling to control the novel Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2), there is an urgency to develop effective control measures …

[HTML][HTML] Mild symptomatic sars-cov-2 p. 1 (b. 1.1. 28) infection in a fully vaccinated 83-year-old man

M Fabiani, K Margiotti, A Viola, A Mesoraca… - Pathogens, 2021 - mdpi.com
The novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) and the
associated coronavirus disease 2019 (COVID-19) continue to spread throughout the world …