The extended granin family: structure, function, and biomedical implications

A Bartolomucci, R Possenti, SK Mahata… - Endocrine …, 2011 - academic.oup.com
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …

Diagnostic tests and biomarkers for pheochromocytoma and extra-adrenal paraganglioma: from routine laboratory methods to disease stratification

G Eisenhofer, AS Tischler, RR de Krijger - Endocrine pathology, 2012 - Springer
The laboratory workup of patients with pheochromocytoma and extra-adrenal
paraganglioma (PPGLs) has traditionally focused on biochemical measurements of tumor …

Hypertension in pheochromocytoma: characteristics and treatment

SM Zuber, V Kantorovich… - … and metabolism clinics, 2011 - endo.theclinics.com
Pheochromocytomas and paragangliomas are tumors derived from chromaffin cells in the
adrenal medulla or extra-adrenal paraganglia. 1 Pheochromocytomas and sympathetic …

A guide to pheochromocytomas and paragangliomas

J Guilmette, PM Sadow - Surgical pathology clinics, 2019 - surgpath.theclinics.com
Pheochromocytomas and extra-adrenal paragangliomas are rare neuroendocrine
neoplasms with characteristic histologic and immunohistochemical features. These tumors …

Molecular and therapeutic advances in the diagnosis and management of malignant pheochromocytomas and paragangliomas

AJ Lowery, S Walsh, EW McDermott… - The …, 2013 - academic.oup.com
Abstract Learning Objectives Discuss the advances in molecular genetics which have
uncovered new hereditary and germline mutations contributing to the development of …

Is secretoneurin a new hormone?

VL Trudeau, CJ Martyniuk, E Zhao, H Hu… - General and …, 2012 - Elsevier
Numerous small potentially bioactive peptides are derived from the selective processing of
the∼ 600 amino acid secretogranin II (SgII) precursor, but only the 31–42 amino acid …

Chromogranin A: a paradoxical player in angiogenesis and vascular biology

KB Helle, A Corti - Cellular and Molecular Life Sciences, 2015 - Springer
Half a century after the discovery of chromogranin A as a secreted product of the
catecholamine storage granules in the bovine adrenal medulla, the physiological role for the …

Dysfunction of calcium-regulated exocytosis at a single-cell level causes catecholamine hypersecretion in patients with pheochromocytoma

S Houy, L Streit, I Drissa, M Rame, C Decraene… - Cancer Letters, 2022 - Elsevier
Neuroendocrine tumors constitute a heterogeneous group of tumors arising from hormone-
secreting cells and are generally associated with a dysfunction of secretion …

Epidermal growth factor and hepatocyte growth factor cooperate to enhance cell proliferation, scatter, and invasion in murine mammary epithelial cells

P Accornero, S Miretti, LS Cucuzza… - Journal of …, 2010 - jme.bioscientifica.com
The pituitary gonadotrophins LH and FSH are responsible for regulation of gametogenesis
in the testis and ovary. Chorionic gonadotrophin (CG), a third closely related glycoprotein …

[HTML][HTML] Regulation of tumor growth by circulating full-length chromogranin A

F Curnis, A Dallatomasina, M Bianco, A Gasparri… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Chromogranin A (CgA), a neuroendocrine secretory protein, and its fragments are present in
variable amounts in the blood of normal subjects and cancer patients. We investigated …