Peptidomics

R Hellinger, A Sigurdsson, W Wu… - Nature Reviews …, 2023 - nature.com
Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Bioinformatics methods for mass spectrometry-based proteomics data analysis

C Chen, J Hou, JJ Tanner, J Cheng - International journal of molecular …, 2020 - mdpi.com
Recent advances in mass spectrometry (MS)-based proteomics have enabled tremendous
progress in the understanding of cellular mechanisms, disease progression, and the …

Unsupervised machine learning for exploratory data analysis in imaging mass spectrometry

N Verbeeck, RM Caprioli… - Mass spectrometry …, 2020 - Wiley Online Library
Imaging mass spectrometry (IMS) is a rapidly advancing molecular imaging modality that
can map the spatial distribution of molecules with high chemical specificity. IMS does not …

Advances in MALDI mass spectrometry imaging single cell and tissues

X Zhu, T Xu, C Peng, S Wu - Frontiers in Chemistry, 2022 - frontiersin.org
Compared with conventional optical microscopy techniques, mass spectrometry imaging
(MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique …

Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research

JL Norris, RM Caprioli - Chemical reviews, 2013 - ACS Publications
Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

MSiReader v1. 0: evolving open-source mass spectrometry imaging software for targeted and untargeted analyses

MT Bokhart, M Nazari, KP Garrard… - Journal of The …, 2017 - ACS Publications
A major update to the mass spectrometry imaging (MSI) software MSiReader is presented,
offering a multitude of newly added features critical to MSI analyses. MSiReader is a free …

Mass spectrometry imaging of biomolecular information

B Spengler - Analytical chemistry, 2015 - ACS Publications
Mass spectrometry imaging (MSI) has gone through a significant change over the last 3
years, the time span of this review. The predominant mass spectrometric method in …

Direct targeted quantitative molecular imaging of neurotransmitters in brain tissue sections

M Shariatgorji, A Nilsson, RJA Goodwin, P Källback… - Neuron, 2014 - cell.com
Current neuroimaging techniques have very limited abilities to directly identify and quantify
neurotransmitters from brain sections. We have developed a molecular-specific approach for …

Absolute quantitative MALDI imaging mass spectrometry: a case of rifampicin in liver tissues

CW Chumbley, ML Reyzer, JL Allen… - Analytical …, 2016 - ACS Publications
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS)
elucidates molecular distributions in thin tissue sections. Absolute pixel-to-pixel quantitation …

Mass spectrometry imaging of plant metabolites–principles and possibilities

N Bjarnholt, B Li, J D'Alvise, C Janfelt - Natural product reports, 2014 - pubs.rsc.org
Covering: up to the end of 2013 New mass spectrometry imaging (MSI) techniques are
gaining importance in the analysis of plant metabolite distributions, and significant …