Diabetes and hypertension: is there a common metabolic pathway?
BMY Cheung, C Li - Current atherosclerosis reports, 2012 - Springer
Diabetes and hypertension frequently occur together. There is substantial overlap between
diabetes and hypertension in etiology and disease mechanisms. Obesity, inflammation …
diabetes and hypertension in etiology and disease mechanisms. Obesity, inflammation …
FTO gene polymorphisms and obesity risk in Chinese population: a meta-analysis
NN Zhao, GP Dong, W Wu, JL Wang, R Ullah… - World journal of …, 2019 - Springer
Background There is tremendous increase in obesity worldwide. Many factors including diet,
life style, genetic, and epigenetic changes contribute to obesity. The fat mass and obesity …
life style, genetic, and epigenetic changes contribute to obesity. The fat mass and obesity …
[HTML][HTML] High dietary saturated fat intake accentuates obesity risk associated with the fat mass and obesity-associated gene in adults
Background: Fat mass and obesity-associated (FTO) is the strongest genetic determinant of
obesity identified to date. Dietary fat is a key environmental factor that may interact with …
obesity identified to date. Dietary fat is a key environmental factor that may interact with …
Maternal metabolic syndrome in pregnancy and child development at age 5: exploring mediating mechanisms using cord blood markers
Background There is limited evidence on how the classification of maternal metabolic
syndrome during pregnancy affects children's developmental outcomes and the possible …
syndrome during pregnancy affects children's developmental outcomes and the possible …
Evidence for Association of an ACCN1 Gene Variant with Response to Lithium Treatment in Sardinian Patients with Bipolar Disorder
A Squassina, M Manchia, J Borg, D Congiu… - …, 2011 - Taylor & Francis
Aims: Bipolar disorder (BD) is a lifelong psychiatric illness characterized by manic and
depressive episodes affecting 1–5% of the general population. Among mood-stabilizing …
depressive episodes affecting 1–5% of the general population. Among mood-stabilizing …
[HTML][HTML] Association of FTO gene variant (rs8050136) with type 2 diabetes and markers of obesity, glycaemic control and inflammation
Background FTO, a gene recently discovered in genomewide associated studies for type 2
diabetes mellitus (T2D), play an important role in the management of energy homeostasis …
diabetes mellitus (T2D), play an important role in the management of energy homeostasis …
Common genetic variation in obesity, lipid transfer genes and risk of Metabolic Syndrome: Results from IDEFICS/I. Family study and meta-analysis
As the prevalence of metabolic syndrome (MetS) in children and young adults is increasing,
a better understanding of genetics that underlie MetS will provide critical insights into the …
a better understanding of genetics that underlie MetS will provide critical insights into the …
Effects of FTO RS9939906 and MC4R RS17782313 on obesity, type 2 diabetes mellitus and blood pressure in patients with hypertension
Background Genetic variants of the FTO gene rs9939609 A/T and the MC4R gene
rs17782313 C/T have been associated with obesity. Individuals with mutations in MC4R …
rs17782313 C/T have been associated with obesity. Individuals with mutations in MC4R …
Genetic variants in FTO associated with metabolic syndrome: a meta- and gene-based analysis
H Wang, S Dong, H Xu, J Qian, J Yang - Molecular biology reports, 2012 - Springer
The objective of this study was to examine the effect of genetic variants in fat mass and
obesity associated (FTO) gene on metabolic syndrome (MetS). A systematic literature search …
obesity associated (FTO) gene on metabolic syndrome (MetS). A systematic literature search …
[HTML][HTML] The influence of genetics on response to treatment with ranibizumab (Lucentis) for age-related macular degeneration: the Lucentis Genotype Study (an …
PJ Francis - Transactions of the American Ophthalmological …, 2011 - ncbi.nlm.nih.gov
Purpose Age-related macular degeneration (AMD) has a complex etiology arising from
genetic and environmental influences. This past decade have seen several genes …
genetic and environmental influences. This past decade have seen several genes …