Few among the millions of fungal species fulfill four basic conditions necessary to infect
humans: high temperature tolerance, ability to invade the human host, lysis and absorption …

Only few Candida species, eg, Candida albicans, Candida glabrata, Candida dubliniensis,
and Candida parapsilosis, are successful colonizers of a human host. Under certain …

Candida albicans is the most common cause of serious fungal disease in humans. Creation
of isogenic null mutants of this diploid organism, which requires sequential gene targeting …

Candida albicans is a commensal fungus of the human gastrointestinal tract and a prevalent
opportunistic pathogen. To examine diversity within this species, extensive genomic and …

Candida albicans is a frequent colonizer of human mucosal surfaces as well as an
opportunistic pathogen. C. albicans is remarkably versatile in its ability to colonize diverse …

Constitutive overexpression of the MDR1 (multidrug resistance) gene, which encodes a
multidrug efflux pump of the major facilitator superfamily, is a frequent cause of resistance to …

Candida albicans has an elaborate, yet efficient, mating system that promotes conjugation
between diploid a and α strains. The product of mating is a tetraploid a/α cell that must …

The genomic plasticity of Candida albicans, a commensal and common opportunistic fungal
pathogen, continues to reveal unexpected surprises. Once thought to be asexual, we now …

Overexpression of the MDR1 gene, encoding a multi‐drug efflux pump of the major facilitator
superfamily, is a major cause of resistance to the widely used antifungal agent fluconazole …

The fungal disease chytridiomycosis, caused by Batrachochytrium dendrobatidis, is
enigmatic because it occurs globally in both declining and apparently healthy (non …