Porcine epidemic diarrhea virus: An updated overview of virus epidemiology, virulence variation patterns and virus–host interactions

Y Zhang, Y Chen, J Zhou, X Wang, L Ma, J Li, L Yang… - Viruses, 2022 - mdpi.com
The porcine epidemic diarrhea virus (PEDV) is a member of the coronavirus family, causing
deadly watery diarrhea in newborn piglets. The global pandemic of PEDV, with significant …

Translational control in virus-infected cells

N Stern-Ginossar, SR Thompson… - Cold Spring …, 2019 - cshperspectives.cshlp.org
As obligate intracellular parasites, virus reproduction requires host cell functions. Despite
variations in genome size and configuration, nucleic acid composition, and their repertoire of …

The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein

S Lu, Q Ye, D Singh, Y Cao, JK Diedrich… - Nature …, 2021 - nature.com
The multifunctional nucleocapsid (N) protein in SARS-CoV-2 binds the~ 30 kb viral RNA
genome to aid its packaging into the 80–90 nm membrane-enveloped virion. The N protein …

Negri bodies and other virus membrane-less replication compartments

Q Nevers, AA Albertini, C Lagaudrière-Gesbert… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Viruses reshape the organization of the cell interior to achieve different steps of their cellular
cycle. Particularly, viral replication and assembly often take place in viral factories where …

G3BP1 inhibits RNA virus replication by positively regulating RIG-I-mediated cellular antiviral response

W Yang, Y Ru, J Ren, J Bai, J Wei, S Fu, X Liu… - Cell death & …, 2019 - nature.com
Retinoic acid-inducible gene I (RIG-I) is a pattern recognition receptor and is involved in the
innate immune response against RNA viruses infection. Here, we demonstrate that the Ras …

Research Progress on the Structure and Function of G3BP

W Kang, Y Wang, W Yang, J Zhang, H Zheng… - Frontiers in …, 2021 - frontiersin.org
Ras-GTPase-activating protein (SH3 domain)-binding protein (G3BP) is an RNA binding
protein. G3BP is a key component of stress granules (SGs) and can interact with many host …

Fractional time-delay mathematical modeling of Oncolytic Virotherapy

P Kumar, VS Erturk, A Yusuf, S Kumar - Chaos, Solitons & Fractals, 2021 - Elsevier
An emerging treatment tool which uses replication-competent viruses to dissipate cancers
without causing deficit to normal tissues, named as oncolytic virotherapy, is discussed in the …

The roles of G3BP1 in human diseases

Y Ge, J Jin, J Li, M Ye, X Jin - Gene, 2022 - Elsevier
Ras-GTPase-activating protein binding protein 1 (G3BP1) is a multifunctional binding
protein involved in a variety of biological functions, including cell proliferation, metastasis …

A little less aggregation a little more replication: Viral manipulation of stress granules

MJ Brownsword, N Locker - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Recent exciting studies have uncovered how membrane‐less organelles, also known as
biocondensates, are providing cells with rapid response pathways, allowing them to re …

Strategies for success. Viral infections and membraneless organelles

A Gaete-Argel, CL Márquez, GP Barriga… - Frontiers in cellular …, 2019 - frontiersin.org
Regulation of RNA homeostasis or “RNAstasis” is a central step in eukaryotic gene
expression. From transcription to decay, cellular messenger RNAs (mRNAs) associate with …