Challenges with the diagnosis and treatment of cerebral radiation necrosis

ST Chao, MS Ahluwalia, GH Barnett… - International Journal of …, 2013 - Elsevier
The incidence of radiation necrosis has increased secondary to greater use of combined
modality therapy for brain tumors and stereotactic radiosurgery. Given that its characteristics …

The diagnosis and treatment of pseudoprogression, radiation necrosis and brain tumor recurrence

K Parvez, A Parvez, G Zadeh - International journal of molecular sciences, 2014 - mdpi.com
Radiation therapy is an important modality used in the treatment of patients with brain
metastatic disease and malignant gliomas. Post-treatment surveillance often involves serial …

[HTML][HTML] A systematic review informing the management of symptomatic brain radiation necrosis after stereotactic radiosurgery and international stereotactic …

B Vellayappan, MJ Lim-Fat, R Kotecha… - International Journal of …, 2024 - Elsevier
Background Radiation necrosis (RN) secondary to stereotactic radiosurgery is a significant
cause of morbidity. The optimal management of corticosteroid-refractory brain RN remains …

Differentiation between radiation necrosis and tumor progression using chemical exchange saturation transfer

H Mehrabian, KL Desmond, H Soliman, A Sahgal… - Clinical Cancer …, 2017 - AACR
Purpose: Stereotactic radiosurgery (SRS) is a common treatment used in patients with brain
metastases and is associated with high rates of local control, however, at the risk of radiation …

Distinguishing true progression from radionecrosis after stereotactic radiation therapy for brain metastases with machine learning and radiomics

L Peng, V Parekh, P Huang, DD Lin, K Sheikh… - International Journal of …, 2018 - Elsevier
Purpose Treatment effect or radiation necrosis after stereotactic radiosurgery (SRS) for brain
metastases is a common phenomenon often indistinguishable from true progression …

[HTML][HTML] Combined FET PET/MRI radiomics differentiates radiation injury from recurrent brain metastasis

P Lohmann, M Kocher, G Ceccon, EK Bauer… - NeuroImage: Clinical, 2018 - Elsevier
Background The aim of this study was to investigate the potential of combined textural
feature analysis of contrast-enhanced MRI (CE-MRI) and static O-(2-[18 F] fluoroethyl)-L …

Current applications of MRI-guided laser interstitial thermal therapy in the treatment of brain neoplasms and epilepsy: a radiologic and neurosurgical overview

R Medvid, A Ruiz, RJ Komotar… - American Journal …, 2015 - Am Soc Neuroradiology
Minimally invasive stereotactic tumor ablation is a viable option for the treatment of benign
and malignant intracranial lesions. Although surgical excision constitutes first-line therapy …

Postradiation imaging changes in the CNS: how can we differentiate between treatment effect and disease progression?

AJ Walker, J Ruzevick, AA Malayeri, D Rigamonti… - Future …, 2014 - Taylor & Francis
A familiar challenge for neuroradiologists and neuro-oncologists is differentiating between
radiation treatment effect and disease progression in the CNS. Both entities are …

Radiation necrosis or tumor progression? A review of the radiographic modalities used in the diagnosis of cerebral radiation necrosis

ZS Mayo, A Halima, JR Broughman, TD Smile… - Journal of neuro …, 2023 - Springer
Purpose Cerebral radiation necrosis is a complication of radiation therapy that can be seen
months to years following radiation treatment. Differentiating radiation necrosis from tumor …

Accuracy of F-DOPA PET and perfusion-MRI for differentiating radionecrotic from progressive brain metastases after radiosurgery

F Cicone, G Minniti, A Romano, A Papa… - European journal of …, 2015 - Springer
Purpose We assessed the performance of 6-[18 F]-fluoro-l-3, 4-dihydroxyphenylalanine (F-
DOPA) PET for differentiating radionecrosis (RN) from tumour progression (PD) in a …