Background Severe bleeding and coagulopathy are serious clinical conditions that are
associated with high mortality. Thromboelastography (TEG) and thromboelastometry …

Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …

Owing to the constantly evolving nature of the medical literature, the Society of Thoracic
Surgeons (STS) clinical practice guidelines periodically undergoes evaluation and updating …

Purpose Contemporary trauma resuscitation prioritizes control of bleeding and uses major
haemorrhage protocols (MHPs) to prevent and treat coagulopathy. We aimed to determine …

The management of perioperative bleeding involves multiple assessments and strategies to
ensure appropriate patient care. Initially, it is important to identify those patients with an …

Improvements in the control of haemorrhage after trauma have resulted in the survival of
many people who would otherwise have died from the initial loss of blood. However, the …

Patient blood management (PBM) is the timely application of evidence-informed medical
and surgical concepts designed to maintain haemoglobin concentration, optimise …

In physiological hemostasis a prompt recruitment of platelets on the vessel damage prevents
the bleeding by the rapid formation of a platelet plug. Qualitative and/or quantitative platelet …

Background Major haemorrhage is a clinical emergency that results in morbidity and
mortality: practice guidance is important to reduce these risks. Delayed recognition of …

Background: Cardiac surgery is frequently complicated by coagulopathic bleeding that is
difficult to optimally manage using standard hemostatic testing. We hypothesized that point …