Over the past decade, we have observed a massive increase in the amount of information
describing protein sequences from a variety of organisms. 1, 2 While this may reflect the …

Many gene sequences in eukaryotic genomes encode entire proteins or large segments of
proteins that lack a well-structured three-dimensional fold. Disordered regions can be highly …

Abstract DisProt (URL: https://disprot. org) is the gold standard database for intrinsically
disordered proteins and regions, providing valuable information about their functions. The …

Abstract The Database of Protein Disorder (DisProt, URL: www. disprot. org) has been
significantly updated and upgraded since its last major renewal in 2007. The current release …

Motivation Capturing long-range interactions between structural but not sequence neighbors
of proteins is a long-standing challenging problem in bioinformatics. Recently, long short …

Background Due to the functional importance of intrinsically disordered proteins or protein
regions, prediction of intrinsic protein disorder from amino acid sequence has become an …

An easy-to-use, versatile and freely available graphic web server, FoldIndex© is described:
it predicts if a given protein sequence is intrinsically unfolded implementing the algorithm of …

Feature selection aims at finding the most relevant features of a problem domain. It is very
helpful in improving computational speed and prediction accuracy. However, identification of …

Regulation, recognition and cell signaling involve the coordinated actions of many players.
To achieve this coordination, each participant must have a valid identification (ID) that is …

Intrinsically disordered or unstructured proteins (or regions in proteins) have been found to
be important in a wide range of biological functions and implicated in many diseases. Due to …