[HTML][HTML] Recent advances and challenges of repurposing nanoparticle-based drug delivery systems to enhance cancer immunotherapy
Cancer immunotherapy is an attractive treatment option under clinical settings. However, the
major challenges of immunotherapy include limited patient response, limited tumor …
major challenges of immunotherapy include limited patient response, limited tumor …
Bacterial inclusion bodies: discovering their better half
U Rinas, E Garcia-Fruitós, JL Corchero… - Trends in biochemical …, 2017 - cell.com
Bacterial inclusion bodies (IBs) are functional, non-toxic amyloids occurring in recombinant
bacteria showing analogies with secretory granules of the mammalian endocrine system …
bacteria showing analogies with secretory granules of the mammalian endocrine system …
Polystyrene nanoplastics accumulate in ZFL cell lysosomes and in zebrafish larvae after acute exposure, inducing a synergistic immune response in vitro without …
The presence of small-sized plastic particles in marine and freshwater environments is a
global problem but their long-term impact on ecosystems and human health is still far from …
global problem but their long-term impact on ecosystems and human health is still far from …
Bacterial inclusion bodies are industrially exploitable amyloids
A De Marco, N Ferrer-Miralles… - FEMS microbiology …, 2019 - academic.oup.com
Understanding the structure, functionalities and biology of functional amyloids is an issue of
emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria …
emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria …
Trends in recombinant protein use in animal production
Recombinant technologies have made possible the production of a broad catalogue of
proteins of interest, including those used for animal production. The most widely studied …
proteins of interest, including those used for animal production. The most widely studied …
Self-assembling ferritin nanoplatform for the development of infectious hematopoietic necrosis virus vaccine
S Ahmadivand, Z Krpetic, MM Martínez… - Frontiers in …, 2024 - frontiersin.org
Self-assembling protein nanoparticles are used as a novel vaccine design platform to
improve the stability and immunogenicity of safe subunit vaccines, while providing broader …
improve the stability and immunogenicity of safe subunit vaccines, while providing broader …
Zebrafish models for the safety and therapeutic testing of nanoparticles with a focus on macrophages
A Pensado-López, J Fernández-Rey, P Reimunde… - Nanomaterials, 2021 - mdpi.com
New nanoparticles and biomaterials are increasingly being used in biomedical research for
drug delivery, diagnostic applications, or vaccines, and they are also present in numerous …
drug delivery, diagnostic applications, or vaccines, and they are also present in numerous …
Magnetic mesoporous silica nanorods loaded with ceria and functionalized with fluorophores for multimodal imaging
Multifunctional magnetic nanocomposites based on mesoporous silica have a wide range of
potential applications in catalysis, biomedicine, or sensing. Such particles combine …
potential applications in catalysis, biomedicine, or sensing. Such particles combine …
A new generation of recombinant polypeptides combines multiple protein domains for effective antimicrobial activity
R Roca-Pinilla, A López-Cano, C Saubi… - Microbial Cell …, 2020 - Springer
Background Although most of antimicrobial peptides (AMPs), being relatively short, are
produced by chemical synthesis, several AMPs have been produced using recombinant …
produced by chemical synthesis, several AMPs have been produced using recombinant …
Fish red blood cells modulate immune genes in response to bacterial inclusion bodies made of TNFα and a G-VHSV fragment
Fish Red-Blood Cells (RBCs) are nucleated cells that can modulate the expression of
different sets of genes in response to stimuli, playing an active role in the homeostasis of the …
different sets of genes in response to stimuli, playing an active role in the homeostasis of the …