[HTML][HTML] Recent advances and challenges of repurposing nanoparticle-based drug delivery systems to enhance cancer immunotherapy

S Lim, J Park, MK Shim, W Um, HY Yoon, JH Ryu… - Theranostics, 2019 - ncbi.nlm.nih.gov
Cancer immunotherapy is an attractive treatment option under clinical settings. However, the
major challenges of immunotherapy include limited patient response, limited tumor …

Bacterial inclusion bodies: discovering their better half

U Rinas, E Garcia-Fruitós, JL Corchero… - Trends in biochemical …, 2017 - cell.com
Bacterial inclusion bodies (IBs) are functional, non-toxic amyloids occurring in recombinant
bacteria showing analogies with secretory granules of the mammalian endocrine system …

Polystyrene nanoplastics accumulate in ZFL cell lysosomes and in zebrafish larvae after acute exposure, inducing a synergistic immune response in vitro without …

I Brandts, M Garcia-Ordoñez, L Tort, M Teles… - Environmental Science …, 2020 - pubs.rsc.org
The presence of small-sized plastic particles in marine and freshwater environments is a
global problem but their long-term impact on ecosystems and human health is still far from …

Bacterial inclusion bodies are industrially exploitable amyloids

A De Marco, N Ferrer-Miralles… - FEMS microbiology …, 2019 - academic.oup.com
Understanding the structure, functionalities and biology of functional amyloids is an issue of
emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria …

Trends in recombinant protein use in animal production

L Gifre, A Arís, À Bach, E Garcia-Fruitós - Microbial cell factories, 2017 - Springer
Recombinant technologies have made possible the production of a broad catalogue of
proteins of interest, including those used for animal production. The most widely studied …

Self-assembling ferritin nanoplatform for the development of infectious hematopoietic necrosis virus vaccine

S Ahmadivand, Z Krpetic, MM Martínez… - Frontiers in …, 2024 - frontiersin.org
Self-assembling protein nanoparticles are used as a novel vaccine design platform to
improve the stability and immunogenicity of safe subunit vaccines, while providing broader …

Zebrafish models for the safety and therapeutic testing of nanoparticles with a focus on macrophages

A Pensado-López, J Fernández-Rey, P Reimunde… - Nanomaterials, 2021 - mdpi.com
New nanoparticles and biomaterials are increasingly being used in biomedical research for
drug delivery, diagnostic applications, or vaccines, and they are also present in numerous …

Magnetic mesoporous silica nanorods loaded with ceria and functionalized with fluorophores for multimodal imaging

J Grzelak, J Gázquez, A Grayston, M Teles… - ACS applied nano …, 2022 - ACS Publications
Multifunctional magnetic nanocomposites based on mesoporous silica have a wide range of
potential applications in catalysis, biomedicine, or sensing. Such particles combine …

A new generation of recombinant polypeptides combines multiple protein domains for effective antimicrobial activity

R Roca-Pinilla, A López-Cano, C Saubi… - Microbial Cell …, 2020 - Springer
Background Although most of antimicrobial peptides (AMPs), being relatively short, are
produced by chemical synthesis, several AMPs have been produced using recombinant …

Fish red blood cells modulate immune genes in response to bacterial inclusion bodies made of TNFα and a G-VHSV fragment

S Puente-Marin, R Thwaite, L Mercado, J Coll… - Frontiers in …, 2019 - frontiersin.org
Fish Red-Blood Cells (RBCs) are nucleated cells that can modulate the expression of
different sets of genes in response to stimuli, playing an active role in the homeostasis of the …