Single-virus tracking: from imaging methodologies to virological applications

SL Liu, ZG Wang, HY Xie, AA Liu, DC Lamb… - Chemical …, 2020 - ACS Publications
Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

HIV: cell binding and entry

CB Wilen, JC Tilton, RW Doms - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
The first step of the human immunodeficiency virus (HIV) replication cycle—binding and
entry into the host cell—plays a major role in determining viral tropism and the ability of HIV …

HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation

MA Checkley, BG Luttge, EO Freed - Journal of molecular biology, 2011 - Elsevier
The HIV-1 envelope (Env) glycoproteins play an essential role in the virus replication cycle
by mediating the fusion between viral and cellular membranes during the entry process. The …

Chikungunya virus cell-to-cell transmission is mediated by intercellular extensions in vitro and in vivo

P Yin, BJ Davenport, JJ Wan, AS Kim… - Nature …, 2023 - nature.com
Chikungunya virus (CHIKV) has recently emerged to cause millions of human infections
worldwide. Infection can induce the formation of long intercellular extensions that project …

[HTML][HTML] Virus entry: open sesame

M Marsh, A Helenius - Cell, 2006 - cell.com
Detailed information about the replication cycle of viruses and their interactions with host
organisms is required to develop strategies to stop them. Cell biology studies, live-cell …

Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response

K Hase, K Kawano, T Nochi, GS Pontes, S Fukuda… - Nature, 2009 - nature.com
The mucosal immune system forms the largest part of the entire immune system, containing
about three-quarters of all lymphocytes and producing grams of secretory IgA daily to protect …

C-type lectins: their network and roles in pathogen recognition and immunity

S Mayer, MK Raulf, B Lepenies - Histochemistry and cell biology, 2017 - Springer
C-type lectins (CTLs) represent the most complex family of animal/human lectins that
comprises 17 different groups. During evolution, CTLs have developed by diversification to …

The reservoir of latent HIV

J Chen, T Zhou, Y Zhang, S Luo, H Chen… - Frontiers in cellular …, 2022 - frontiersin.org
The persistence of latent reservoir of the human immunodeficiency virus (HIV) is currently
the major challenge in curing HIV infection. After HIV infects the human body, the latent HIV …

DC-SIGN: escape mechanism for pathogens

Y van Kooyk, TBH Geijtenbeek - Nature Reviews Immunology, 2003 - nature.com
Dendritic cells (DCs) are crucial in the defence against pathogens. Invading pathogens are
recognized by Toll-like receptors (TLRs) and receptors such as C-type lectins expressed on …

Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer

PY Pan, G Ma, KJ Weber, J Ozao-Choy, G Wang, B Yin… - Cancer research, 2010 - AACR
Immune tolerance to tumors is often associated with accumulation of myeloid-derived
suppressor cells (MDSC) and an increase in the number of T-regulatory cells (Treg). In …