Single-virus tracking: from imaging methodologies to virological applications
Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …
HIV: cell binding and entry
The first step of the human immunodeficiency virus (HIV) replication cycle—binding and
entry into the host cell—plays a major role in determining viral tropism and the ability of HIV …
entry into the host cell—plays a major role in determining viral tropism and the ability of HIV …
HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation
MA Checkley, BG Luttge, EO Freed - Journal of molecular biology, 2011 - Elsevier
The HIV-1 envelope (Env) glycoproteins play an essential role in the virus replication cycle
by mediating the fusion between viral and cellular membranes during the entry process. The …
by mediating the fusion between viral and cellular membranes during the entry process. The …
Chikungunya virus cell-to-cell transmission is mediated by intercellular extensions in vitro and in vivo
Chikungunya virus (CHIKV) has recently emerged to cause millions of human infections
worldwide. Infection can induce the formation of long intercellular extensions that project …
worldwide. Infection can induce the formation of long intercellular extensions that project …
[HTML][HTML] Virus entry: open sesame
M Marsh, A Helenius - Cell, 2006 - cell.com
Detailed information about the replication cycle of viruses and their interactions with host
organisms is required to develop strategies to stop them. Cell biology studies, live-cell …
organisms is required to develop strategies to stop them. Cell biology studies, live-cell …
Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response
K Hase, K Kawano, T Nochi, GS Pontes, S Fukuda… - Nature, 2009 - nature.com
The mucosal immune system forms the largest part of the entire immune system, containing
about three-quarters of all lymphocytes and producing grams of secretory IgA daily to protect …
about three-quarters of all lymphocytes and producing grams of secretory IgA daily to protect …
C-type lectins: their network and roles in pathogen recognition and immunity
S Mayer, MK Raulf, B Lepenies - Histochemistry and cell biology, 2017 - Springer
C-type lectins (CTLs) represent the most complex family of animal/human lectins that
comprises 17 different groups. During evolution, CTLs have developed by diversification to …
comprises 17 different groups. During evolution, CTLs have developed by diversification to …
The reservoir of latent HIV
J Chen, T Zhou, Y Zhang, S Luo, H Chen… - Frontiers in cellular …, 2022 - frontiersin.org
The persistence of latent reservoir of the human immunodeficiency virus (HIV) is currently
the major challenge in curing HIV infection. After HIV infects the human body, the latent HIV …
the major challenge in curing HIV infection. After HIV infects the human body, the latent HIV …
DC-SIGN: escape mechanism for pathogens
Y van Kooyk, TBH Geijtenbeek - Nature Reviews Immunology, 2003 - nature.com
Dendritic cells (DCs) are crucial in the defence against pathogens. Invading pathogens are
recognized by Toll-like receptors (TLRs) and receptors such as C-type lectins expressed on …
recognized by Toll-like receptors (TLRs) and receptors such as C-type lectins expressed on …
Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer
PY Pan, G Ma, KJ Weber, J Ozao-Choy, G Wang, B Yin… - Cancer research, 2010 - AACR
Immune tolerance to tumors is often associated with accumulation of myeloid-derived
suppressor cells (MDSC) and an increase in the number of T-regulatory cells (Treg). In …
suppressor cells (MDSC) and an increase in the number of T-regulatory cells (Treg). In …