Dopamine, immunity, and disease
B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - Elsevier
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …
regulating many processes including reward, movement, and cognition. Dopamine also …
Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models
Tissue/organ shortage is a major medical challenge due to donor scarcity and patient
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …
NLRP3 inflammasome—a key player in antiviral responses
C Zhao, W Zhao - Frontiers in immunology, 2020 - frontiersin.org
The NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome is an
oligomeric complex comprised of the NOD-like receptor NLRP3, the adaptor ASC, and …
oligomeric complex comprised of the NOD-like receptor NLRP3, the adaptor ASC, and …
[HTML][HTML] Inflammasome signalling in brain function and neurodegenerative disease
The mammalian CNS is an intricate and fragile structure, which on one hand is open to
change in order to store information, but on the other hand is vulnerable to damage from …
change in order to store information, but on the other hand is vulnerable to damage from …
Global prevalence and burden of HIV-associated neurocognitive disorder: a meta-analysis
Objective To characterize the prevalence and burden of HIV-associated neurocognitive
disorder (HAND) and assess associated factors in the global population with HIV. Methods …
disorder (HAND) and assess associated factors in the global population with HIV. Methods …
Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOVER initiative
H Bonilla, MJ Peluso, K Rodgers, JA Aberg… - Frontiers in …, 2023 - frontiersin.org
Although most individuals recover from acute SARS-CoV-2 infection, a significant number
continue to suffer from Post-Acute Sequelae of SARS-CoV-2 (PASC), including the …
continue to suffer from Post-Acute Sequelae of SARS-CoV-2 (PASC), including the …
Neuroimmune axes of the blood–brain barriers and blood–brain interfaces: bases for physiological regulation, disease states, and pharmacological interventions
Central nervous system (CNS) barriers predominantly mediate the immune-privileged status
of the brain, and are also important regulators of neuroimmune communication. It is …
of the brain, and are also important regulators of neuroimmune communication. It is …
Astrocyte senescence: evidence and significance
J Cohen, C Torres - Aging cell, 2019 - Wiley Online Library
Astrocytes participate in numerous aspects of central nervous system (CNS) physiology
ranging from ion balance to metabolism, and disruption of their physiological roles can …
ranging from ion balance to metabolism, and disruption of their physiological roles can …
Inflammation at the crossroads of COVID-19, cognitive deficits and depression
NML e Silva, FGQ Barros-Aragão, FG De Felice… - …, 2022 - Elsevier
Acute neurological alterations have been associated with SARS-CoV-2 infection.
Additionally, it is becoming clear that coronavirus disease 2019 (COVID-19) survivors may …
Additionally, it is becoming clear that coronavirus disease 2019 (COVID-19) survivors may …
Cognitive impairment in people living with HIV: consensus recommendations for a new approach
Current approaches to classifying cognitive impairment in people living with HIV can
overestimate disease burden and lead to ambiguity around disease mechanisms. The 2007 …
overestimate disease burden and lead to ambiguity around disease mechanisms. The 2007 …