Microglia and astrocytes produce several cytokines including interleukin 1 (IL1) and tumor
necrosis factor alpha (TNFα), which have pleiotropic effects in the immune and nervous …

Participation of nitric oxide (NO) in the autonomic innervation of rat and guinea pig hearts
was investigated by applying the NADPH diaphorase technique and immunohistochemistry …

Abstract Serotonin (5‐HT) plays a major role at the spinal level by modulating most spinal
functions through several receptor subtypes including the 5‐HT2A receptor. To gain further …

Several lines of evidence indicate that peripheral 5-HT2A receptors are involved in the
development of inflammatory and neuropathic pain. However, their localization in sensory …

This manuscript reviews state-of-the-art mass spectrometric (MS) methodology for the
qualitative (amino acid sequence determination) and quantitative analysis of opioid …

The metallopeptidase enkephalinase known to participate in the inactivation of endogenous
enkephalins and, possibly, other neuropeptides such as tachykinins, was visualized by …

A convenient, versatile and straightforward synthesis of a novel heterotrifunctional peptide-
based linker molecule is described. This generic bio-labelling reagent contains an amine …

A new enzyme immunometric assay of small haptens containing primary aminogroups
(thyroxine, MW 777; substance P, MW 1347; endothelin, MW 2492) is described. The …

The topography of the binding site of a monoclonal anti‐substance P antibody directed
toward the C‐terminal pentapeptide of substance P, Arg‐Pro‐Lys‐Pro‐Gln‐Gln‐Phe‐Phe …

Cerebral vasospasm after subarachnoid hemorrhage may result partially from the imbalance
between vasodilator and vasoconstrictor factors. The vasodilator peptides substance P and …