NMR spectroscopy for metabolomics research

AH Emwas, R Roy, RT McKay, L Tenori, E Saccenti… - Metabolites, 2019 - mdpi.com
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …

Plant metabolomics: a new strategy and tool for quality evaluation of Chinese medicinal materials

Q Xiao, X Mu, J Liu, B Li, H Liu, B Zhang, P Xiao - Chinese Medicine, 2022 - Springer
The present quality control method of Chinese medicinal materials (CMM) has obvious
deficiency, which cannot be compatible with the multi-target and multi-component …

Chromatographic separation techniques and data handling methods for herbal fingerprints: a review

C Tistaert, B Dejaegher, Y Vander Heyden - Analytica chimica acta, 2011 - Elsevier
As herbal medicines have an important position in health care systems worldwide, their
current assessment and quality control are a major bottleneck. Over the past decade, major …

Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review

AH Emwas, C Luchinat, P Turano, L Tenori, R Roy… - Metabolomics, 2015 - Springer
The metabolic composition of human biofluids can provide important diagnostic and
prognostic information. Among the biofluids most commonly analyzed in metabolomic …

Recommendations and standardization of biomarker quantification using NMR-based metabolomics with particular focus on urinary analysis

AH Emwas, R Roy, RT McKay, D Ryan… - Journal of proteome …, 2016 - ACS Publications
NMR-based metabolomics has shown considerable promise in disease diagnosis and
biomarker discovery because it allows one to nondestructively identify and quantify large …

Similarity analyses of chromatographic herbal fingerprints: a review

M Goodarzi, PJ Russell, Y Vander Heyden - Analytica Chimica Acta, 2013 - Elsevier
Herbal medicines are becoming again more popular in the developed countries because
being “natural” and people thus often assume that they are inherently safe. Herbs have also …

Quality control of herbal medicines: From traditional techniques to state-of-the-art approaches

LC Klein-Junior, MR de Souza, J Viaene… - Planta …, 2021 - thieme-connect.com
Herbal medicines are important options for the treatment of several illnesses. Although their
therapeutic applicability has been demonstrated throughout history, several concerns about …

A critical assessment of feature selection methods for biomarker discovery in clinical proteomics

C Christin, HCJ Hoefsloot, AK Smilde… - Molecular & Cellular …, 2013 - ASBMB
In this paper, we compare the performance of six different feature selection methods for LC-
MS-based proteomics and metabolomics biomarker discovery—t test, the Mann–Whitney …

Impact of Drying Methods on Phenolic Components and Antioxidant Activity of Sea Buckthorn (Hippophae rhamnoides L.) Berries from Different Varieties in China

Y Li, P Li, K Yang, Q He, Y Wang, Y Sun, C He, P Xiao - Molecules, 2021 - mdpi.com
Sea buckthorn berries are rich in bioactive compounds and can be used for medicine and
food. The variety and drying method used have an important influence on quality. In this …

Metabolomics Study on Quality Control and Discrimination of Three Curcuma Species based on Gas Chromatograph–Mass Spectrometry

Z Xiang, X Wang, X Cai, S Zeng - Phytochemical Analysis, 2011 - Wiley Online Library
Introduction Metabonomic analysis is an important molecular phenotyping method for
characterising plant ecotypic variations; hence, it may become a powerful tool for quality …