Abstract The 4, 4′-diaminodiphenyl sulfone (DDS), also known as dapsone, is traditionally
used as a potent anti-bacterial agent in clinical management of leprosy. For decades …

Background Sub-anesthetic ketamine has rapid-onset effects for the treatment of major
depressive disorder (MDD). However, the mechanism underlying ketamine's antidepressant …

Scopolamine is a well-known pharmacological agent responsible for causing memory
impairment in animals, as well as oxidative stress and neuroinflammation inducer which …

Nitric oxide (NO), a signaling molecule, regulates multiple biological functions, including a
variety of physiological and pathological processes. In this regard, NO participates in …

Allopurinol, a uric-acid-lowering medication, has shown its efficacy in several studies
suggesting that allopurinol can be prescribed as adjunctive cure meant for intractable …

Background Non-deleterious episodes of seizure preconditioning can efficiently increase
the brain's resistance to the consequent severe status epilepticus (SE). In the present …

Background Early post-stroke seizure frequently occurs in stroke survivors within the first few
days and is associated with poor functional outcomes. Therefore, efficient treatments of such …

Itching is an unpleasant sensation on the skin that could negatively impact the quality of life.
Over the years, many non-pharmacological and pharmacological approaches have been …

Citral, a common monoterpene found in numerous plants, is an interesting compound that
has been shown to have various biological activities. Although it is widely distributed in …

Carvone, a natural monoterpene, has been identified in various plants, giving them a
characteristic scent. Enantiomers (R-(–) and S-(+)) reveal specific biological activities that …