Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics

G Paglia, AJ Smith, G Astarita - Mass Spectrometry Reviews, 2022 - Wiley Online Library
Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations

DG Delafield, G Lu, CJ Kaminsky, L Li - TrAC Trends in Analytical …, 2022 - Elsevier
Mass spectrometry-based biomolecular analyses have become permanent fixtures of
academic, industrial, and clinical research settings. The rise in utilization of mass …

Mixed plastics waste valorization through tandem chemical oxidation and biological funneling

KP Sullivan, AZ Werner, KJ Ramirez, LD Ellis… - Science, 2022 - science.org
Mixed plastics waste represents an abundant and largely untapped feedstock for the
production of valuable products. The chemical diversity and complexity of these materials …

Ion mobility collision cross-section atlas for known and unknown metabolite annotation in untargeted metabolomics

Z Zhou, M Luo, X Chen, Y Yin, X Xiong, R Wang… - Nature …, 2020 - nature.com
The metabolome includes not just known but also unknown metabolites; however,
metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility …

Advanced analytical and informatic strategies for metabolite annotation in untargeted metabolomics

Y Cai, Z Zhou, ZJ Zhu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Liquid chromatography–mass spectrometry (LC–MS)-based untargeted metabolomics is
constantly challenged by large-scale and unambiguous metabolite annotation in complex …

Recent advances in analytical strategies for mass spectrometry-based lipidomics

T Xu, C Hu, Q Xuan, G Xu - Analytica chimica acta, 2020 - Elsevier
Lipids are vital biological molecules and play multiple roles in cellular function of
mammalian organisms such as cellular membrane anchoring, signal transduction, material …

Ion mobility spectrometry in food analysis: Principles, current applications and future trends

M Hernández-Mesa, D Ropartz, AM García-Campaña… - Molecules, 2019 - mdpi.com
In the last decade, ion mobility spectrometry (IMS) has reemerged as an analytical
separation technique, especially due to the commercialization of ion mobility mass …

AllCCS2: Curation of ion mobility collision cross-section atlas for small molecules using comprehensive molecular representations

H Zhang, M Luo, H Wang, F Ren, Y Yin… - Analytical …, 2023 - ACS Publications
The development of ion mobility–mass spectrometry (IM–MS) has revolutionized the
analysis of small molecules, such as metabolomics, lipidomics, and exposome studies. The …

A novel hybrid scan approach enabling the ion-mobility separation and the alternate data-dependent and data-independent acquisitions (HDDIDDA): Its combination …

H Wang, X Wang, X Xu, Y Hu, X Li, X Shi, S Wang… - Analytica Chimica …, 2022 - Elsevier
Data-dependent acquisition (DDA) and data-independent acquisition (DIA)-based MS n
strategies are extensively applied in metabolites characterization. DDA gives accurate MS n …

Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain

T Li, Y Yin, Z Zhou, J Qiu, W Liu, X Zhang, K He… - Nature …, 2021 - nature.com
Aberrant sterol lipid metabolism is associated with physiological dysfunctions in the aging
brain and aging-dependent disorders such as neurodegenerative diseases. There is an …