Ancient wheat species and human health: Biochemical and clinical implications

M Dinu, A Whittaker, G Pagliai, S Benedettelli… - The Journal of nutritional …, 2018 - Elsevier
Wheat is the major staple food in many diets. Based on the increase in worldwide mortality
attributable to diet-related chronic diseases, there is an increasing interest in identifying …

Integrin signaling in atherosclerosis

AC Finney, KY Stokes, CB Pattillo, AW Orr - Cellular and Molecular Life …, 2017 - Springer
Atherosclerosis, a chronic lipid-driven inflammatory disease affecting large arteries,
represents the primary cause of cardiovascular disease in the world. The local remodeling of …

[HTML][HTML] Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism

LM Tsujikawa, L Fu, S Das, C Halliday, BD Rakai… - Clinical …, 2019 - Springer
Abstract Background Apabetalone (RVX-208) is a bromodomain and extraterminal protein
inhibitor (BETi) that in phase II trials reduced the relative risk (RR) of major adverse cardiac …

Cytokines and microRNA in coronary artery disease

H Mirzaei, GA Ferns, A Avan, MG Mobarhan - Advances in clinical …, 2017 - Elsevier
Cardiovascular disease (CVD) is a major health problem globally. The high incidence and
case fatality of CVD are, to a large extent, a consequence of its late diagnosis and lack of …

[HTML][HTML] Nanotechnology for targeted therapy of atherosclerosis

S Hossaini Nasr, X Huang - Frontiers in Pharmacology, 2021 - frontiersin.org
Atherosclerosis is the major cause of heart attack and stroke that are the leading causes of
death in the world. Nanomedicine is a powerful tool that can be engineered to target …

Hesperetin and its sulfate and glucuronide metabolites inhibit TNF-α induced human aortic endothelial cell migration and decrease plasminogen activator inhibitor-1 …

JA Giménez-Bastida, A González-Sarrías, F Vallejo… - Food & function, 2016 - pubs.rsc.org
Epidemiological, clinical and preclinical studies have reported the protection offered by
citrus consumption, mainly orange, against cardiovascular diseases, which is primarily …

Multiplex cytokine profiling of stimulated mouse splenocytes using a cytometric bead-based immunoassay platform

JS Lehmann, A Zhao, B Sun, W Jiang, S Ji - JoVE (Journal of Visualized …, 2017 - jove.com
Bead-based immunoassays employ the same basic principle as sandwich immunoassays.
Capture beads, which can be differentiated by size and internal allophycocyanin (APC) …

[HTML][HTML] An organic khorasan wheat-based replacement diet improves risk profile of patients with acute coronary syndrome: a randomized crossover trial

A Whittaker, F Sofi, MLE Luisi, E Rafanelli, C Fiorillo… - Nutrients, 2015 - mdpi.com
Khorasan wheat is an ancient grain with previously reported health benefits in clinically
healthy subjects. The aim of this study was to examine whether a replacement diet, thereby …

Circulating microRNA expression profiling and bioinformatics analysis of patients with coronary artery disease by RNA sequencing

Z Zhong, W Zhong, Q Zhang, Q Zhang… - Journal of clinical …, 2020 - Wiley Online Library
Background MicroRNAs play a vital role in coronary artery disease. Abnormal expression of
microRNAs has been found to be associated with the occurrence of CAD. Methods We …

S100A12 in renal and cardiovascular diseases

A Nazari, H Khorramdelazad, G Hassanshahi, AS Day… - Life sciences, 2017 - Elsevier
Expression of S100A12, a small calcium-binding protein, by neutrophils and monocytes/
macrophages induces proinflammatory responses via ligation with the receptor for …