Evidenced-based guidelines for management of infants and children with community-
acquired pneumonia (CAP) were prepared by an expert panel comprising clinicians and …

Streptococcus pneumoniae is the most common cause of community-acquired pneumonia,
meningitis, and bacteremia in children and adults. Invasive pneumococcal disease (IPD) …

Background Changes in invasive pneumococcal disease (IPD) incidence were evaluated
after 7 years of 7-valent pneumococcal conjugate vaccine (PCV7) use in US children …

Background: The 13-valent pneumococcal conjugate vaccine (PCV13) was introduced for
routine administration to infants and children in 2010 in the United States. We have …

Background Although recent reports suggest that the incidence of parapneumonic empyema
has increased in several regions of the USA, national trends in disease burden are …

ContextWith routine childhood vaccination using heptavalent pneumococcal conjugate
vaccine, one concern has been the potential for emergence and expansion of replacement …

Streptococcus pneumoniae can asymptomatically colonize the nasopharynx and cause a
diverse range of illnesses. This clinical spectrum from colonization to invasive …

Background. The incidence of childhood pneumonia decreased following introduction of 7-
valent pneumococcal conjugate vaccine (PCV7) in the United States. Recent regional …

BACKGROUND: Empyema is a suppurative infection of the pleural space. Without prompt
treatment, it can result in significant hospital stays, more invasive treatments as it …

OBJECTIVE: To determine if the incidence of empyema among children in the United States
has changed since the introduction of the pneumococcal conjugate vaccine in 2000 …