How has research into cytokine interactions and their role in driving immune responses impacted our understanding of periodontitis?

PM Preshaw, JJ Taylor - Journal of clinical periodontology, 2011 - Wiley Online Library
Preshaw PM, Taylor JJ. How has research into cytokine interactions and their role in driving
immune responses impacted our understanding of periodontitis? J Clin Periodontol 2011; …

Mapping the pathogenesis of periodontitis: a new look

KS Kornman - Journal of periodontology, 2008 - Wiley Online Library
Chronic adult periodontitis is a bacterially induced chronic inflammatory disease that
destroys the connective tissue and bone that support teeth. Concepts of the specific …

Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association? A scientific statement from the American Heart …

PB Lockhart, AF Bolger, PN Papapanou… - Circulation, 2012 - Am Heart Assoc
A link between oral health and cardiovascular disease has been proposed for more than a
century. Recently, concern about possible links between periodontal disease (PD) and …

Gum Bug, Leave My Heart Alone!”—Epidemiologic and Mechanistic Evidence Linking Periodontal Infections and Atherosclerosis

M Kebschull, RT Demmer… - Journal of dental …, 2010 - journals.sagepub.com
Evidence from epidemiologic studies suggests that periodontal infections are independently
associated with subclinical and clinical atherosclerotic vascular disease. Although the …

Periodontal disease and incident type 2 diabetes: results from the First National Health and Nutrition Examination Survey and its epidemiologic follow-up study

RT Demmer, DR Jacobs Jr, M Desvarieux - Diabetes care, 2008 - Am Diabetes Assoc
OBJECTIVE—Type 2 diabetes and periodontal disease are known to be associated, but the
temporality of this relationship has not been firmly established. We investigated whether …

Periodontal infection, systemic inflammation, and insulin resistance: results from the continuous National Health and Nutrition Examination Survey (NHANES) 1999 …

RT Demmer, A Squillaro, PN Papapanou… - Diabetes …, 2012 - Am Diabetes Assoc
OBJECTIVE Adverse microbial exposures might contribute to diabetogenesis. We
hypothesized that clinical periodontal disease (a manifestation of microbial exposures in …

Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima‐media thickness

S Piconi, D Trabattoni, C Luraghi, E Perilli… - The FASEB …, 2009 - Wiley Online Library
Several cohort studies reported a relation of cardiovascular events and periodontal disease.
In particular, Porphyromonas gingivalis is associated with the development of …

Heterogeneity of systemic inflammatory responses to periodontal therapy

JH Behle, MH Sedaghatfar, RT Demmer… - Journal of clinical …, 2009 - Wiley Online Library
Aims: We investigated the effect of comprehensive periodontal therapy on the levels of
multiple systemic inflammatory biomarkers. Material and Methods: Thirty patients with …

[HTML][HTML] Chronic skin-specific inflammation promotes vascular inflammation and thrombosis

Y Wang, H Gao, CM Loyd, W Fu, D Diaconu… - Journal of investigative …, 2012 - Elsevier
Patients with psoriasis have systemic and vascular inflammation and are at increased risk
for myocardial infarction, stroke, and cardiovascular death. However, the underlying …

Bacterial invasion of vascular cell types: vascular infectology and atherogenesis

E Kozarov - Future cardiology, 2012 - Taylor & Francis
To portray the chronic inflammation in atherosclerosis, leukocytic cell types involved in the
immune response to invading pathogens are often the focus. However, atherogenesis is a …