The effects of dipeptidyl peptidase-4 inhibition on microvascular diabetes complications

A Avogaro, GP Fadini - Diabetes care, 2014 - Am Diabetes Assoc
We performed a review of the literature to determine whether the dipeptidyl peptidase-4
inhibitors (DPP4-I) may have the capability to directly and positively influence diabetic …

An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: potential implications in cardiovascular disease

J Zhong, X Rao, S Rajagopalan - Atherosclerosis, 2013 - Elsevier
The introduction of dipeptidyl peptidase 4 (DPP4) inhibitors for the treatment of Type 2
diabetes acknowledges the fundamental importance of incretin hormones in the regulation …

Methods of reducing the risk of a cardiovascular event in a subject on statin therapy

P Soni - US Patent 9,610,272, 2017 - Google Patents
In various embodiments, the present invention provides methods of reducing the risk of a
cardiovascular event in a subject on statin therapy and, in particular, a method of reducing …

Comparative clinical pharmacokinetics of dipeptidyl peptidase-4 inhibitors

LK Golightly, CC Drayna, MT McDermott - Clinical pharmacokinetics, 2012 - Springer
Abstract Dipeptidyl peptidase-4 (DPP-4) inhibitors collectively comprise a presently unique
form of disease management for persons with type 2 diabetes mellitus. The aim of this …

Compositions comprising EPA and obeticholic acid and methods of use thereof

JS Zakrzewski - US Patent 9,814,733, 2017 - Google Patents
US9814733B2 - Compositions comprising EPA and obeticholic acid and methods of use
thereof - Google Patents US9814733B2 - Compositions comprising EPA and obeticholic …

Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same

M Manku, I Osterloh, P Wicker, R Braeckman… - US Patent …, 2021 - Google Patents
The present invention relates to, inter alia, pharmaceutical compositions comprising EPA
and one or more cardiovascular agents, and to therapeutic methods for treating various …

Methods of reducing the risk of a cardiovascular event in a subject on statin therapy

P Soni - US Patent 9,918,954, 2018 - Google Patents
In various embodiments, the present invention provides methods of reducing the risk of a
cardiovascular event in a subject on statin therapy and, in particular, a method of reducing …

Incretins-based therapies and their cardiovascular effects: new game-changers for the management of patients with diabetes and cardiovascular disease

F Bernardini, A Nusca, F Coletti, Y La Porta, M Piscione… - Pharmaceutics, 2023 - mdpi.com
Atherosclerosis is the leading cause of death worldwide, especially in patients with type 2
diabetes mellitus (T2D). GLP-1 receptor agonists and DPP-4 inhibitors were demonstrated …

Methods of reducing the risk of a cardiovascular event in a subject on statin therapy

P Soni - US Patent 9,623,001, 2017 - Google Patents
In various embodiments, the present invention provides methods of reducing the risk of a
cardiovascular event in a subject on statin therapy and, in particular, a method of reducing …

Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof

JS Zakrzewski - US Patent 9,624,492, 2017 - Google Patents
US9624492B2 - Compositions comprising eicosapentaenoic acid and mipomersen and
methods of use thereof - Google Patents US9624492B2 - Compositions comprising …