[HTML][HTML] Porous scaffolds for bone regeneration

N Abbasi, S Hamlet, RM Love, NT Nguyen - Journal of science: advanced …, 2020 - Elsevier
Globally, bone fractures due to osteoporosis occur every 20 s in people aged over 50 years.
The significant healthcare costs required to manage this problem are further exacerbated by …

Macrophage phenotypes in tissue repair and the foreign body response: Implications for biomaterial-based regenerative medicine strategies

KE Martin, AJ García - Acta biomaterialia, 2021 - Elsevier
Macrophages are a highly heterogeneous and plastic population of cells that are crucial for
tissue repair and regeneration. This has made macrophages a particularly attractive target …

Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

Dealing with the foreign‐body response to implanted biomaterials: strategies and applications of new materials

D Zhang, Q Chen, C Shi, M Chen, K Ma… - Advanced Functional …, 2021 - Wiley Online Library
Foreign‐body response caused by implanted biomaterials seriously impedes the function of
implants and is a major obstacle to the development of implantable biomaterials and …

Macrophage related chronic inflammation in non-healing wounds

M Li, Q Hou, L Zhong, Y Zhao, X Fu - Frontiers in Immunology, 2021 - frontiersin.org
Persistent hyper-inflammation is a distinguishing pathophysiological characteristic of chronic
wounds, and macrophage malfunction is considered as a major contributor thereof. In this …

Endometrial and menstrual blood mesenchymal stem/stromal cells: biological properties and clinical application

M Bozorgmehr, S Gurung, S Darzi, S Nikoo… - Frontiers in cell and …, 2020 - frontiersin.org
A highly proliferative mesenchymal stem/stromal cell (MSC) population was recently
discovered in the dynamic, cyclically regenerating human endometrium as clonogenic …

Domesticating the foreign body response: Recent advances and applications

O Veiseh, AJ Vegas - Advanced drug delivery reviews, 2019 - Elsevier
The foreign body response is an immunological process that leads to the rejection of
implanted devices and presents a fundamental challenge to their performance, durability …

Scaffold strategies for modulating immune microenvironment during bone regeneration

J He, G Chen, M Liu, Z Xu, H Chen, L Yang… - Materials Science and …, 2020 - Elsevier
Implanted bone scaffolds often fail to successfully integrate with the host tissue because they
do not elicit a favorable immune reaction. Properties of bone scaffold not only provide …

3D bioprinted endometrial stem cells on melt electrospun poly ε-caprolactone mesh for pelvic floor application promote anti-inflammatory responses in mice

K Paul, S Darzi, G McPhee, MP Del Borgo… - Acta biomaterialia, 2019 - Elsevier
Endometrial mesenchymal stem/stromal cells (eMSCs) exhibit excellent regenerative
capacity in the endometrial lining of the uterus following menstruation and high proliferative …

Strategies to address mesenchymal stem/stromal cell heterogeneity in immunomodulatory profiles to improve cell-based therapies

CM Dunn, S Kameishi, DW Grainger, T Okano - Acta Biomaterialia, 2021 - Elsevier
Mesenchymal stromal cells (MSCs) have gained immense attention over the past two
decades due to their multipotent differentiation potential and pro-regenerative and …