Plant‐derived extracellular vesicles: Recent advancements and current challenges on their use for biomedical applications

MQ Lian, WH Chng, J Liang, HQ Yeo… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) represent a diverse class of lipid bilayer membrane vesicles
released by both animal and plant cells. These ubiquitous vesicles are involved in …

Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: present and future

SR Li, QW Man, X Gao, H Lin, J Wang… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐bilayer membrane structures secreted by most cell
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …

Piezotronic and piezo‐phototronic effects on sonodynamic disease therapy

Y Zhao, T Huang, X Zhang, Y Cui, L Zhang, L Li… - …, 2023 - Wiley Online Library
With the development of engineered nanomaterials and nanomedicines, utilization of
nanomaterials to generate excessive reactive oxygen species under exogenous ultrasound …

Antioxidant peptides, the guardian of life from oxidative stress

Y Zhu, K Wang, X Jia, C Fu, H Yu… - Medicinal Research …, 2024 - Wiley Online Library
Reactive oxygen species (ROS) are produced during oxidative metabolism in aerobic
organisms. Under normal conditions, ROS production and elimination are in a relatively …

Oxidative stress in amyotrophic lateral sclerosis: pathophysiology and opportunities for pharmacological intervention

T Cunha-Oliveira, L Montezinho… - Oxidative medicine …, 2020 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease or Charcot
disease, is a fatal neurodegenerative disease that affects motor neurons (MNs) and leads to …

ROS signaling cascades: dual regulations for osteoclast and osteoblast

H Tao, G Ge, X Liang, W Zhang, H Sun… - Acta Biochimica et …, 2020 - academic.oup.com
Accumulating evidence indicates that intracellular reactive oxygen species (ROS)
production is highly involved in bone homeostasis by intervening osteoclast or osteoblast …

[HTML][HTML] Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine

M Li, F Fang, M Sun, Y Zhang, M Hu, J Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …

Extracellular vesicles as signaling mediators and disease biomarkers across biological barriers

P Simeone, G Bologna, P Lanuti… - International journal of …, 2020 - mdpi.com
Extracellular vesicles act as shuttle vectors or signal transducers that can deliver specific
biological information and have progressively emerged as key regulators of organized …

Astrocytes as a therapeutic target in alzheimer's disease–comprehensive review and recent developments

M Rodríguez-Giraldo, RE González-Reyes… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …

Dendrobium officinale polysaccharide triggers mitochondrial disorder to induce colon cancer cell death via ROS-AMPK-autophagy pathway

K Zhang, X Zhou, J Wang, Y Zhou, W Qi, H Chen… - Carbohydrate …, 2021 - Elsevier
The homeostasis between mitochondrial function and autophagy is crucial to the
physiological activity of cancer cells, and its mechanism is conducive to the development of …