Mind the gap: from neurons to networks to outcomes in multiple sclerosis

DT Chard, AAS Alahmadi, B Audoin… - Nature Reviews …, 2021 - nature.com
MRI studies have provided valuable insights into the structure and function of neural
networks, particularly in health and in classical neurodegenerative conditions such as …

[HTML][HTML] Task-and resting-state fMRI studies in multiple sclerosis: From regions to systems and time-varying analysis. Current status and future perspective

MA Rocca, MM Schoonheim, P Valsasina… - Neuroimage: Clinical, 2022 - Elsevier
Multiple sclerosis (MS) is a neurological disorder affecting the central nervous system and
features extensive functional brain changes that are poorly understood but relate strongly to …

Thalamic injury and cognition in multiple sclerosis

M Amin, D Ontaneda - Frontiers in Neurology, 2021 - frontiersin.org
Multiple sclerosis (MS) produces demyelination and degeneration in both gray and white
matter. Both cortical and deep gray matter injury is observed during the course of MS …

A systematic review of resting-state functional MRI connectivity changes and cognitive impairment in multiple sclerosis

D Jandric, A Doshi, R Scott, D Paling, D Rog… - Brain …, 2022 - liebertpub.com
Introduction: Cognitive impairment in multiple sclerosis (MS) is increasingly being
investigated with resting-state functional MRI (rs-fMRI) functional connectivity (FC). However …

Thalamic nuclei volumes and their relationships to neuroperformance in multiple sclerosis: a cross‐sectional structural MRI study

N Bergsland, RHB Benedict, MG Dwyer… - Journal of Magnetic …, 2021 - Wiley Online Library
Background Although reduced thalamic volume is associated with multiple sclerosis (MS)‐
related clinical impairment, the role of individual thalamic nuclei remains poorly understood …

Granger causality analysis in combination with directed network measures for classification of MS patients and healthy controls using task-related fMRI

F Azarmi, SNM Ashtiani, A Shalbaf, H Behnam… - Computers in biology …, 2019 - Elsevier
Several studies have already assessed brain network variations in multiple sclerosis (MS)
patients and healthy controls (HCs). The underlying neural system's functioning is …

MRI biomarkers of disease progression and conversion to secondary-progressive multiple sclerosis

E Tavazzi, R Zivadinov, MG Dwyer… - Expert Review of …, 2020 - Taylor & Francis
Introduction Conventional imaging measures remain a key clinical tool for the diagnosis
multiple sclerosis (MS) and monitoring of patients. However, most measures used in the …

[HTML][HTML] Functional connectivity dynamics reflect disability and multi-domain clinical impairment in patients with relapsing-remitting multiple sclerosis

A Romanello, S Krohn, N Von Schwanenflug… - NeuroImage: Clinical, 2022 - Elsevier
Abstract Background & Aim Multiple sclerosis (MS) is an autoimmune disease of the central
nervous system associated with deficits in cognitive and motor functioning. While structural …

Vascular aspects of multiple sclerosis: emphasis on perfusion and cardiovascular comorbidities

D Jakimovski, M Topolski, AV Genovese… - Expert review of …, 2019 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and
neurodegenerative disease of the central nervous system. Over the last two decades, more …

Neural distinctiveness of fatigue and low sleep quality in multiple sclerosis

AL Ruiz‐Rizzo, P Bublak, S Kluckow… - European Journal of …, 2022 - Wiley Online Library
Background and purpose Fatigue and low sleep quality in multiple sclerosis (MS) are
closely related symptoms. Here, the associations between the brain's functional connectivity …