[HTML][HTML] Update of pathophysiology and management of diabetic kidney disease

YC Lin, YH Chang, SY Yang, KD Wu, TS Chu - Journal of the formosan …, 2018 - Elsevier
Diabetic kidney disease (DKD) is a major cause of morbidity and mortality in patients with
diabetes mellitus and the leading cause of end-stage renal disease in the world. The most …

Epidemiology of breast cancer, a paradigm of the “common soil” hypothesis

L Iacoviello, M Bonaccio, G de Gaetano… - Seminars in cancer …, 2021 - Elsevier
Breast cancer is the leading cause of death in women aged 20–50 years, with some
geographical difference. The yearly incidence of the disease is increasing while the related …

Lifestyle and chronic pain across the lifespan: an inconvenient truth?

J Nijs, E D'Hondt, P Clarys, T Deliens, A Polli, A Malfliet… - Pm&r, 2020 - Wiley Online Library
Chronic pain has a tremendous personal and socioeconomic impact and remains difficult to
treat. Therefore, it is important to provide an update on the current understanding regarding …

Importancia de la actividad física

AL Perea-Caballero, GE López-Navarrete… - Salud …, 2020 - medigraphic.com
Todos recomendamos realizar Actividad Física, pero realmente deberíamos de reflexionar
qué tanto sabemos entorno al músculo y por ende porqué hay que mantenernos activos …

Premature physiologic aging as a paradigm for understanding increased risk of adverse health across the lifespan of survivors of childhood cancer

KK Ness, JL Kirkland, MM Gramatges… - Journal of Clinical …, 2018 - ascopubs.org
The improvement in survival of childhood cancer observed across the past 50 years has
resulted in a growing acknowledgment that simply extending the lifespan of survivors is not …

[HTML][HTML] Microglial phagocytosis of neurons: diminishing neuronal loss in traumatic, infectious, inflammatory, and autoimmune CNS disorders

SF Yanuck - Frontiers in psychiatry, 2019 - frontiersin.org
Errors in neuron-microglial interaction are known to lead to microglial phagocytosis of live
neurons and excessive neuronal loss, potentially yielding poorer clinical outcomes. Factors …

Epi-drugs and Epi-miRs: moving beyond current cancer therapies

R Salarinia, A Sahebkar, M Peyvandi… - Current cancer drug …, 2016 - ingentaconnect.com
Epigenetic modifications determine phenotypic characteristics in a reversible, stable and
genotype-independent manner. Epigenetic modifications mainly encompass CpG island …

Inhibition of EZH2 (enhancer of zeste homolog 2) attenuates neuroinflammation via H3k27me3/SOCS3/TRAF6/NF-κB (trimethylation of histone 3 lysine 27/suppressor …

Y Luo, Y Fang, R Kang, C Lenahan, M Gamdzyk… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Neuroinflammation has been proven to play an important role in
the pathogenesis of early brain injury after subarachnoid hemorrhage (SAH). EZH2 …

Effects of exercise training on physical and psychosocial health in children with chronic respiratory disease: a systematic review and meta-analysis

B Joschtel, SR Gomersall, S Tweedy… - BMJ open sport & …, 2018 - bmjopensem.bmj.com
Introduction Chronic disease in children is increasing, including the prevalence of chronic
respiratory diseases such as asthma, cystic fibrosis (CF), bronchiectasis and …

Epigenetics and obesity cardiomyopathy: from pathophysiology to prevention and management

Y Zhang, J Ren - Pharmacology & therapeutics, 2016 - Elsevier
Uncorrected obesity has been associated with cardiac hypertrophy and contractile
dysfunction. Several mechanisms for this cardiomyopathy have been identified, including …