Gait impairments in Parkinson's disease

A Mirelman, P Bonato, R Camicioli, TD Ellis… - The Lancet …, 2019 - thelancet.com
Gait impairments are among the most common and disabling symptoms of Parkinson's
disease. Nonetheless, gait is not routinely assessed quantitatively but is described in …

A systematic review on exercise and training-based interventions for freezing of gait in Parkinson's disease

M Gilat, P Ginis, D Zoetewei… - npj Parkinson's …, 2021 - nature.com
Freezing of gait (FOG) in Parkinson's disease (PD) causes severe patient burden despite
pharmacological management. Exercise and training are therefore advocated as important …

Cholinergic system changes of falls and freezing of gait in Parkinson's disease

NI Bohnen, P Kanel, Z Zhou, RA Koeppe… - Annals of …, 2019 - Wiley Online Library
Objective Postural instability and gait difficulties (PIGDs) represent debilitating disturbances
in Parkinson's disease (PD). Past acetylcholinesterase positron emission tomography (PET) …

Imaging the limbic system in Parkinson's disease—a review of limbic pathology and clinical symptoms

M Banwinkler, H Theis, S Prange, T van Eimeren - Brain sciences, 2022 - mdpi.com
The limbic system describes a complex of brain structures central for memory, learning, as
well as goal directed and emotional behavior. In addition to pathological studies, recent …

A novel CERNNE approach for predicting Parkinson's Disease-associated genes and brain regions based on multimodal imaging genetics data

X Bi, X Hu, Y Xie, H Wu - Medical Image Analysis, 2021 - Elsevier
The detection and pathogenic factors analysis of Parkinson's disease (PD) has a practical
significance for its diagnosis and treatment. However, the traditional research paradigms are …

Discussion of research priorities for gait disorders in Parkinson's disease

NI Bohnen, RM Costa, WT Dauer, SA Factor… - Movement …, 2022 - Wiley Online Library
Gait and balance abnormalities develop commonly in Parkinson's disease and are among
the motor symptoms most disabling and refractory to dopaminergic or other treatments …

Cognition and freezing of gait in Parkinson's disease: A systematic review and meta-analysis

AS Monaghan, E Gordon, L Graham, E Hughes… - Neuroscience & …, 2023 - Elsevier
Freezing of gait (FOG) is a common and disabling symptom in people with Parkinson's
Disease (PwPD). Although cognition is thought to be worse in PwPD who freeze, a …

[HTML][HTML] Neuroimaging advances in Parkinson's disease with freezing of gait: a systematic review

K Bharti, A Suppa, S Tommasin, A Zampogna… - NeuroImage: Clinical, 2019 - Elsevier
Freezing of gait (FOG) is a paroxysmal gait disorder that often occurs at advanced stages of
Parkinson's disease (PD). FOG consists of abrupt walking interruption and severe difficulty in …

Relationships between gait and emotion in Parkinson's disease: a narrative review

L Avanzino, G Lagravinese, G Abbruzzese, E Pelosin - Gait & posture, 2018 - Elsevier
Background Disturbance of gait is a key feature of Parkinson's disease (PD) and has a
negative impact on quality of life. Deficits in cognition and sensorimotor processing impair …

Cognitively challenging agility boot camp program for freezing of gait in Parkinson disease

LA King, M Mancini, K Smulders… - … and neural repair, 2020 - journals.sagepub.com
Introduction. It is well documented that freezing of gait (FoG) episodes occur in situations
that are mentally challenging, such as dual tasks, consistent with less automatic control of …