Inflammation-related prognostic markers in resected hepatocellular carcinoma

F Giannone, N Slovic, P Pessaux, C Schuster… - Frontiers in …, 2023 - frontiersin.org
Hepatocellular carcinoma is usually detected late and therapeutic options are unsatisfactory.
Despite marked progress in patient care, HCC remains among the deadliest cancers world …

T cell exhaustion and senescence for ovarian cancer immunotherapy

J Zhao, Z Wang, Y Tian, J Ning, H Ye - Seminars in Cancer Biology, 2024 - Elsevier
Ovarian cancer is a common gynecological malignancy, and its treatment remains
challenging. Although ovarian cancer may respond to immunotherapy because of …

Integration of Chemoinformatics and Multi-Omics Analysis Defines ECT2 as a Potential Target for Cancer Drug Therapy

MA Soltan, MA Eldeen, BH Sajer, RFA Abdelhameed… - Biology, 2023 - mdpi.com
Simple Summary Cancer is a leading cause of death worldwide and continuous efforts are
exerted to develop novel biomarkers and therapeutic agents that could help in early …

Oncogenic potential of replication factor C subunit 4: correlations with tumor progression and assessment of potential inhibitors

M Alaa Eldeen, F Mamdouh, WK Abdulsahib, RA Eid… - Pharmaceuticals, 2024 - mdpi.com
Replication Factor C Subunit 4 (RFC4), an oncogene implicated in many human cancers,
has yet to be extensively studied in many cancer types to determine its expression patterns …

FOXM1 transcriptional regulation of RacGAP1 activates the PI3K/AKT signaling pathway to promote the proliferation, migration, and invasion of cervical cancer cells

H Yao, J Li, D Zhou, X Pan, Y Chu, J Yin - International Journal of Clinical …, 2024 - Springer
Background Cervical cancer (CC) is the most common gynecological tumor disease in
women, which occurs at the junction of cervical squamous columnar epithelium. We …

Beauvericin Immunotoxicity Prevention by Gentiana lutea L. Flower In Vitro

G Di Matteo, A Cimbalo, L Manyes, L Mannina - Toxins, 2023 - mdpi.com
Beauvericin (BEA) is an emerging mycotoxin produced by some species of Fusarium genera
that widely contaminates food and feed. Gentiana lutea is a protected medicinal plant known …

Hub gene identification and immune infiltration analysis in hepatocellular carcinoma: Computational approach

S Pulakuntla, SA Singh, VD Reddy - In Silico Pharmacology, 2024 - Springer
In the case of hepatocellular carcinoma, there is a need to find novel immune biomarkers to
predict cancer prognosis, which will help prolong patient survival. On the basis of these …

Cyclin Dependent Kinase Inhibitor 2A Genetic and Epigenetic Alterations Interfere with Several Immune Components and Predict Poor Clinical Outcome

MA Soltan, AA Alhanshani, AA Shati, YA Alqahtani… - Biomedicines, 2023 - mdpi.com
Cyclin dependent kinase inhibitor 2A (CDKN2A) is a well-known tumor suppressor gene as
it functions as a cell cycle regulator. While several reports correlate the malfunction of …

[HTML][HTML] Global trends of single cell sequence associated in cancer from 2011 to 2024: A bibliometric analysis

X Wu, J Fan, X Zhang, T Li, J Song - Heliyon, 2024 - Elsevier
Objective Exploring the different molecular and clinicopathological features of nodal cancer
based on single cell sequencing can reveal the intertumoral heterogeneity in cancer, and …

[HTML][HTML] Identification of prognostic biomarkers of invasive ductal carcinoma by an integrated bioinformatics approach

A Marrugo-Padilla, J Márquez-Lázaro… - …, 2023 - f1000research.com
Background: Invasive ductal carcinoma (IDC) is the most common type of breast cancer (BC)
worldwide. Nowadays, due to its heterogeneity and high capacity for metastasis, it is …