LOX-1: regulation, signaling and its role in atherosclerosis
Atherosclerosis has long been known to be a chronic inflammatory disease. In addition,
there is intense oxidative stress in atherosclerosis resulting from an imbalance between the …
there is intense oxidative stress in atherosclerosis resulting from an imbalance between the …
Role of LOX-1 (lectin-like oxidized low-density lipoprotein receptor 1) as a cardiovascular risk predictor: mechanistic insight and potential clinical use
J Barreto, SK Karathanasis, A Remaley… - … , and vascular biology, 2021 - Am Heart Assoc
Atherosclerosis, the underlying cause of cardiovascular disease (CVD), is a worldwide
cause of morbidity and mortality. Reducing ApoB-containing lipoproteins—chiefly, LDL (low …
cause of morbidity and mortality. Reducing ApoB-containing lipoproteins—chiefly, LDL (low …
Targeting LOX‐1 in atherosclerosis and vasculopathy: current knowledge and future perspectives
Abstract LOX‐1 (lectin‐like oxidized low‐density lipoprotein receptor‐1; also known as
OLR1) is the dominant receptor that recognizes and internalizes oxidized low‐density …
OLR1) is the dominant receptor that recognizes and internalizes oxidized low‐density …
Modulation of endothelial function by Toll like receptors
Endothelial cells (EC) are able to actively control vascular permeability, coagulation, blood
pressure and angiogenesis. Most recently, a role for endothelial cells in the immune …
pressure and angiogenesis. Most recently, a role for endothelial cells in the immune …
The induction of endothelial autophagy and its role in the development of atherosclerosis
Y Hua, J Zhang, Q Liu, J Su, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
Increasing attention is now being paid to the important role played by autophagic flux in
maintaining normal blood vessel walls. Endothelial cell dysfunction initiates the …
maintaining normal blood vessel walls. Endothelial cell dysfunction initiates the …
The role of toll-like receptors in atherothrombotic cardiovascular disease
Toll-like receptors (TLRs) are dominant components of the innate immune system. Activated
by both pathogen-associated molecular patterns and damage-associated molecular …
by both pathogen-associated molecular patterns and damage-associated molecular …
Circular RNA circ_0003645 silencing alleviates inflammation and apoptosis via the NF-κB pathway in endothelial cells induced by oxLDL
M Qin, W Wang, H Zhou, X Wang, F Wang, H Wang - Gene, 2020 - Elsevier
Atherosclerosis (AS) is a serious threat to the cardiovascular system. Circular RNA
circ_0003645 was found to be differentially expressed in the process of AS. Our study tried …
circ_0003645 was found to be differentially expressed in the process of AS. Our study tried …
[HTML][HTML] ApoA-I mimetics reduce systemic and gut inflammation in chronic treated HIV
Novel therapeutic strategies are needed to attenuate increased systemic and gut
inflammation that contribute to morbidity and mortality in chronic HIV infection despite potent …
inflammation that contribute to morbidity and mortality in chronic HIV infection despite potent …
LOX-1 and TLR4 affect each other and regulate the generation of ROS in A. fumigatus keratitis
X Gao, G Zhao, C Li, J Lin, N Jiang, Q Wang… - International …, 2016 - Elsevier
Purpose To explore the relationship between LOX-1 and TLR4 in Aspergillus fumigatus (A.
fumigatus) keratitis. To determine LOX-1 and TLR4 can affect each other and regulate …
fumigatus) keratitis. To determine LOX-1 and TLR4 can affect each other and regulate …
[HTML][HTML] Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression
F Olivares-Silva, R Landaeta, P Aránguiz… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and
growth factors released in cardiac tissue in cardiac injury events, such as myocardial …
growth factors released in cardiac tissue in cardiac injury events, such as myocardial …