Design of pressure-driven microfluidic networks using electric circuit analogy
This article reviews the application of electric circuit methods for the analysis of pressure-
driven microfluidic networks with an emphasis on concentration-and flow-dependent …
driven microfluidic networks with an emphasis on concentration-and flow-dependent …
Concentration gradient generation methods based on microfluidic systems
X Wang, Z Liu, Y Pang - RSC advances, 2017 - pubs.rsc.org
Various concentration gradient generation methods based on microfluidic systems are
summarized in this paper. The review covers typical structural characteristics, gradient …
summarized in this paper. The review covers typical structural characteristics, gradient …
Biological applications of microfluidic gradient devices
Molecular gradients play an important role in diverse physiological and pathological
phenomena such as immune response, wound healing, development and cancer …
phenomena such as immune response, wound healing, development and cancer …
An integrated microfluidics platform with high-throughput single-cell cloning array and concentration gradient generator for efficient cancer drug effect screening
Background Tumor cell heterogeneity mediated drug resistance has been recognized as the
stumbling block of cancer treatment. Elucidating the cytotoxicity of anticancer drugs at single …
stumbling block of cancer treatment. Elucidating the cytotoxicity of anticancer drugs at single …
Enzyme kinetic measurements using a droplet-based microfluidic system with a concentration gradient
In this paper, we propose a microfluidic device that is capable of generating a concentration
gradient followed by parallel droplet formation within channels with a simple T-junction …
gradient followed by parallel droplet formation within channels with a simple T-junction …
Controlling mass transport in microfluidic devices
JS Kuo, DT Chiu - Annual Review of Analytical Chemistry, 2011 - annualreviews.org
Microfluidic platforms offer exquisite capabilities in controlling mass transport for biological
studies. In this review, we focus on recent developments in manipulating chemical …
studies. In this review, we focus on recent developments in manipulating chemical …
Rapid generation of spatially and temporally controllable long-range concentration gradients in a microfluidic device
The ability to rapidly generate concentration gradients of diffusible molecules has important
applications in many chemical and biological studies. Here we established spatially and …
applications in many chemical and biological studies. Here we established spatially and …
Inverse design of microfluidic concentration gradient generator using deep learning and physics-based component model
This paper presents a new paradigm of deep neural network (DNN) for the inverse design of
microfluidic concentration gradient generators (µCGGs) with complex network topology. In …
microfluidic concentration gradient generators (µCGGs) with complex network topology. In …
Preparation of arrays of cell spheroids and spheroid-monolayer cocultures within a microfluidic device
T Okuyama, H Yamazoe, N Mochizuki… - Journal of bioscience …, 2010 - Elsevier
This study describes a novel method for generation of an array of three-dimensional (3D)
multicellular spheroids within a microchannel in patterned cultures containing one or …
multicellular spheroids within a microchannel in patterned cultures containing one or …
Surrogate-based optimization with adaptive sampling for microfluidic concentration gradient generator design
This paper presents a surrogate-based optimization (SBO) method with adaptive sampling
for designing microfluidic concentration gradient generators (μCGGs) to meet prescribed …
for designing microfluidic concentration gradient generators (μCGGs) to meet prescribed …