A marine-based meriolin (3-pyrimidinylazaindole) derivative (4ab) targets PI3K/AKT/mTOR pathway inducing cell cycle arrest and apoptosis in Molt-4 cells
Background: Cyclin-dependent kinases play a central role in the control of cell division and
therefore it is not surprising that cancer exhibits some features that disturb the normal …
therefore it is not surprising that cancer exhibits some features that disturb the normal …
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MD Hendrychová - theses.cz
Over the last 30 years a number of small-molecule inhibitors of cyclin-dependent kinases
(CDK) have been discovered. Some of them have been approved for the treatment of cancer …
(CDK) have been discovered. Some of them have been approved for the treatment of cancer …