Virus–receptor interactions play a key regulatory role in viral host range, tissue tropism, and
viral pathogenesis. Viruses utilize elegant strategies to attach to one or multiple receptors …

More than 80 different adenovirus (AdV) types infect humans through the respiratory, ocular,
or gastrointestinal tracts. They cause acute clinical mani-festations or persist under humoral …

Abstract Simian virus 40 (SV40) is unusual among animal viruses in that it enters cells
through caveolae, and the internalized virus accumulates in a smooth endoplasmic …

Adenovirus type 2 (Ad2) binds the coxsackie B virus Ad receptor and is endocytosed upon
activation of the αv integrin coreceptors. Here, we demonstrate that expression of dominant …

Viruses have long served as tools in molecular and cellular biology to study a variety of
complex cellular processes. Currently, there is a revived interest in virus entry into animal …

Abstract Adenovirus type 2 (Ad2) imports its DNA genome through the nuclear pore complex
(NPC) of cells in interphase for viral production. Here we identify the NPC-filament protein …

Many human adenovirus (Ad) serotypes use the coxsackie B virus-Ad receptor (CAR).
Recently, CD46 was suggested to be a receptor of species B Ad serotype 11 (Ad11), Ad14 …

Viral DNA trafficking in cells has large impacts on physiology and disease development.
Current methods lack the resolution and accuracy to visualize and quantify viral DNA …

To develop nonviral gene vectors that are sufficient for clinical application, it is necessary to
understand why and to what extent nonviral vectors are inferior to viral vectors, which in …

Nuclear targeting of adenovirus is mediated by the microtubule‐dependent, minus‐end‐
directed motor complex dynein/dynactin, in competition with plus‐end‐directed motility. We …