A forward-looking review of seizure prediction
We conclude the review with an exercise in wishful thinking, which asks what the ideal
seizure prediction dataset would look like and how these data should be manipulated to …
seizure prediction dataset would look like and how these data should be manipulated to …
[HTML][HTML] Critical slowing down as a biomarker for seizure susceptibility
The human brain has the capacity to rapidly change state, and in epilepsy these state
changes can be catastrophic, resulting in loss of consciousness, injury and even death …
changes can be catastrophic, resulting in loss of consciousness, injury and even death …
Seizure prediction: science fiction or soon to become reality?
DR Freestone, PJ Karoly, ADH Peterson… - Current neurology and …, 2015 - Springer
This review highlights recent developments in the field of epileptic seizure prediction. We
argue that seizure prediction is possible; however, most previous attempts have used data …
argue that seizure prediction is possible; however, most previous attempts have used data …
[HTML][HTML] Distance to criticality undergoes critical transition before epileptic seizure attacks
Epilepsy is a common neurological disorder characterized by recurring seizures, but its
underlying mechanisms remain poorly understood. Despite extensive research, there are …
underlying mechanisms remain poorly understood. Despite extensive research, there are …
Focus on desynchronization rather than excitability: a new strategy for intraencephalic electrical stimulation
D de Castro Medeiros, MFD Moraes - Epilepsy & Behavior, 2014 - Elsevier
Epilepsy is a severely debilitating brain disease, often associated with premature death,
which has an urgent need for alternative methods of treatment. In fact, roughly 25% of …
which has an urgent need for alternative methods of treatment. In fact, roughly 25% of …
[HTML][HTML] On temporal scale-free non-periodic stimulation and its mechanisms as an infinite improbability drive of the brain's functional connectogram
Rationalized development of electrical stimulation (ES) therapy is of paramount importance.
Not only it will foster new techniques and technologies with increased levels of safety …
Not only it will foster new techniques and technologies with increased levels of safety …
[HTML][HTML] The endocannabinoid system activation as a neural network desynchronizing mediator for seizure suppression
The understanding that hyper-excitability and hyper-synchronism in epilepsy are
indissociably bound by a cause-consequence relation has only recently been challenged …
indissociably bound by a cause-consequence relation has only recently been challenged …
The epileptic amygdala: toward the development of a neural prosthesis by temporally coded electrical stimulation
VR Cota, BMB Drabowski… - Journal of …, 2016 - Wiley Online Library
Many patients with epilepsy do not obtain proper control of their seizures through
conventional treatment. We review aspects of the pathophysiology underlying epileptic …
conventional treatment. We review aspects of the pathophysiology underlying epileptic …
[HTML][HTML] Epilepsy as a dynamical system, a most needed paradigm shift in epileptology
The idea of the epileptic brain being highly excitable and facilitated to synchronic activity has
guided pharmacological treatment since the early twentieth century. Although tackling …
guided pharmacological treatment since the early twentieth century. Although tackling …
Home-cage odors spatial cues elicit theta phase/gamma amplitude coupling between olfactory bulb and dorsal hippocampus
RR Pena, D de Castro Medeiros… - Neuroscience, 2017 - Elsevier
The brain oscillations may play a critical role in synchronizing neuronal assemblies in order
to establish appropriate sensory-motor integration. In fact, studies have demonstrated phase …
to establish appropriate sensory-motor integration. In fact, studies have demonstrated phase …