The signaling lymphocyte activation molecule (SLAM)-associated protein, SAP, was first
identified as the protein affected in most cases of X-linked lymphoproliferative (XLP) …

SAP (SLAM-associated protein) was identified in 1998 as an adaptor molecule involved in
the intracellular signaling pathways elicited through the cell surface receptor SLAM and as …

CD4 T cell help is critical for the generation and maintenance of germinal centers (GCs), and
T follicular helper (T FH) cells are the CD4 T cell subset required for this process. Signaling …

Mutations that affect the adaptor molecule SLAM-associated protein (SAP) underlie the
primary immunodeficiency disease X-linked lymphoproliferative syndrome. SAP is required …

The nine SLAM‐family genes, SLAMF1–9, a subfamily of the immunoglobulin superfamily,
encode differentially expressed cell‐surface receptors of hematopoietic cells. Engagement …

X-linked lymphoproliferative disease is caused by mutations affecting SH2D1A/SAP, an
adaptor that recruits Fyn to signal lymphocyte activation molecule (SLAM)-related receptors …

Abstract Background and Objectives In the present paper we report that SAP, an
intracytoplasmic molecule that is involved in cell signaling, is an immunohistologic marker …

Signaling lymphocytic activating molecule (SLAM) family receptors and SLAM‐associated
protein (SAP)‐related adapters play several important roles in the immune system. Natural …

Ewing's sarcoma-associated transcript 2 (EAT-2) is an Src homology 2 domain-containing
intracellular adaptor related to signaling lymphocytic activation molecule (SLAM) …

Signaling lymphocytic activation molecule (SLAM) family receptors mediate important
regulatory signals in immune cells, as a result of their exquisite ability to associate with …