This review examined a collection of studies regarding the molecular properties of some
polyene antibiotic molecules as well as their properties in solution and in particular …

Multiple human diseases ensue from a hereditary or acquired deficiency of iron-transporting
protein function that diminishes transmembrane iron flux in distinct sites and directions …

Loss-of-function mutations in the cystic fibrosis transmembrane conductance regulator
(CFTR) compromise epithelial HCO3− and Cl− secretion, reduce airway surface liquid pH …

The review summarizes recent advances in the synthesis of new derivatives of polyene
macrolide antibiotics by chemical modification and genetic engineering methods, results of …

Candida glabrata is intrinsically less susceptible to azoles, and resistance to echinocandins
and reduced susceptibility (RS) to amphotericin B (AMB) have also been detected. The …

Herein we report that an imidazole‐decorated cationic amphiphile derived from the pseudo‐
disaccharide nebramine has potent antifungal activity against strains of Candida glabrata …

Nowadays, organic salts and ionic liquids (OSILs) containing active pharmaceutical
ingredients (APIs) are being explored as drug delivery systems in modern therapies (OSILs …

Patients with multiple comorbidities are often administered simultaneously or sequentially
antifungals and antibacterial agents, without full knowledge of the consequences of drug …

A21 (2) is a new polyene macrolide Amphotericin B amide antibiotic derived from
amphotericin B AmB (1), which has been tested extensively on preclinical trials showing the …

Over the last 50 years, the number of patients with mycotic infections has gradually
increased. Amphotericin-B is a gold-standard drug used in serious systemic fungal …