We review the use of molecular dynamics (MD) simulation as a drug design tool in the
context of the role that the lipid membrane can play in drug action, ie, the interaction …

Cancer is a significant global socioeconomic burden, as millions of new cases and deaths
occur annually. In 2020, almost 10 million cancer deaths were recorded worldwide …

Cannabichromene (CBC) is a nonpsychoactive phytocannabinoid well-known for its wide-
ranging health advantages. However, there is limited knowledge regarding its human …

Cytochrome (CYP) enzymes catalyze the metabolic reactions of endogenous and
exogenous compounds. The superfamily of enzymes is found across many organisms …

Abstract Cytochromes P450 (CYP), enzymes involved in the metabolism of endogenous and
xenobiotic substrates, provide an excellent model system to study how membrane proteins …

Cholesterol, a significant constituent of the endoplasmic reticulum membrane, exerts a
substantial effect on the membrane's biophysical and mechanical properties. Cholesterol …

Plant NADPH-dependent cytochrome P450 reductase (CPR) is a multidomain enzyme that
donates electrons for hydroxylation reactions catalyzed by class II cytochrome P450 …

Cytochrome P450 reductase (CPR) is a NADPH-dependent membrane-bound
oxidoreductase found in the endoplasmic reticulum (ER) and is the main redox partner for …

Interactions of membrane-bound mammalian cytochromes P450 (CYPs) with NADPH-
cytochrome P450 oxidoreductase (POR), which are required for metabolism of xenobiotics …

Bioenergy sorghums (Sorghum bicolor (L.) Moench) are cultivated to produce large volumes
of biomass. In the context of bioenergy production, lignin has been the focus of much …