Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Over the past two decades, compelling evidence has emerged indicating that immune
mechanisms can contribute to the pathogenesis of major depressive disorder (MDD) and …

Microglia are resident macrophages of the CNS that are involved in its development,
homeostasis and response to infection and damage. Microglial activation is a common …

Microglia, the primary resident immune cell type, constitute a key population of glia in the
retina. Recent evidence indicates that microglia play significant functional roles in the retina …

Glial cell types were classified less than 100 years ago by del Rio-Hortega. For instance, he
correctly surmised that microglia in pathologic central nervous system (CNS) were …

The role of immune activation in psychiatric disorders has attracted considerable attention
over the past two decades, contributing to the rise of a new era for psychiatry. Microglia, the …

Poor prognosis is often expected after the treatment of intracerebral haemorrhage (ICH)
when the approach lacks effective neuroprotective interventions. Minocycline (Mino) is a …

Evidence from epidemiological, clinical, and biological research resulted in the immune
hypothesis: the hypothesis that immune system dysfunction is involved in the …

Activation of microglia and expression of the inflammatory cytokine interleukin-1 (IL-1) in the
CNS have become almost synonymous with neuroinflammation. In numerous studies …

Maternal immune activation (MIA) during pregnancy has been linked to an increased risk of
developing psychiatric pathologies in later life. This link may be bridged by a defective …